Insights to Preventive Dentistry via Salivary Defensin Peptide: Evaluating B-Defensins for Caries Control and Periodontal Disease Prevention :A Systematic Review and Meta-Analysis

Insights to Preventive Dentistry via Salivary Defensin Peptide: Evaluating B-Defensins for Caries Control and Periodontal Disease Prevention :A Systematic Review and Meta-Analysis

Background: Salivary β-defensins form an essential part of oral immune system activity since they lead microbial balance control and help prevent dental caries and periodontal diseases. This systematic review and meta-analysis examine the role of salivary β-defensins in preventive dentistry by eval...

Full description

Saved in:

Bibliographic Details
Main Authors:	Manzar Anwar Khan, Muhammad Mustafa, Mehwish Munawar, Ashar Hussain, Muhammad Amin Sahito, Khurram Anwar, Fatima Ali
Format:	Article
Language:	English
Published:	ziauddin University 2025-07-01
Series:	Pakistan Journal of Medicine and Dentistry
Subjects:	β-Defensins, Dental Caries Prevention Periodontal Disease Systematic Review Meta-Analysis
Online Access:	https://ojs.zu.edu.pk/pjmd/article/view/3687
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Defensin-Mediated Oral Immunity: A Systematic Review and Meta-Analysis of DEFB1 Expression in Preventive Dentistry Strategies
by: Rehana Kausar, et al.
Published: (2025-07-01)

Comparison of salivary beta-defensin-1 levels in patients with periodontitis before and after phase I periodontal therapy
by: Somaye Ansari Moghadam, et al.
Published: (2024-05-01)

Comparison of salivary statherin and beta-defensin-2 levels, oral health behaviors, and demographic factors in children with and without early childhood caries
by: Maryam Koopaie, et al.
Published: (2025-05-01)

Advances in plant defensins
by: LIAO Qian-sheng, et al.
Published: (2003-01-01)

Disrupting SARS-CoV-2: molecular dynamics insights into the role of human β-defensin 2 and α-defensin 5 peptides in membrane structure alteration
by: M.A. Dashti, et al.
Published: (2024-12-01)

Soluble FcγRIIIb (CD16b) and Alpha Defensin as Markers of Neutrophils Activation in Periodontal Disease
by: Fatima Sabah Jasim, et al.
Published: (2025-07-01)

Immunomodulatory Effects of the Tobacco Defensin NaD1
by: Ekaterina I. Finkina, et al.
Published: (2024-11-01)

Goat specific synthesized antimicrobial peptide β-defensin improves post-thaw sperm fertility
by: MANISH KUMAR, et al.
Published: (2025-07-01)

Detection of chimeric alpha-defensin transcripts and peptides in mouse Paneth cells
by: Steven Timmermans, et al.
Published: (2025-02-01)

Designing an optimized theta-defensin peptide for HIV therapy using in-silico approaches
by: Mosalanejad Zahra, et al.
Published: (2025-03-01)

Insights to Preventive Dentistry by Evaluating Lactoferrin for Caries Control and Periodontal Disease Prevention
by: Rehana Kausar, et al.
Published: (2025-04-01)

THE STUDY OF REGULARITIES OF INDUCTION OF IL-8 SYNTHESIS BY NEUTROPHIL DEFENSINS IN VITRO
by: Y. V. Chaly, et al.
Published: (2014-07-01)

Defensin: The immune system regulatory factor against peripheral nerve disease
by: Tiantian Qi, et al.
Published: (2025-03-01)

Elevated serum levels of cathelicidin and β-defensin 2 are associated with basal cell carcinoma
by: Marta Fijałkowska, et al.
Published: (2021-10-01)

Heterologous expression of the Stellaria media plant defensin SmD1 in Escherichia coli
by: Yiyi Qiu, et al.
Published: (2025-06-01)

Snake venom defensins: Defining the structural and functional characteristics of the toxin family
by: David Melendez-Martinez, et al.
Published: (2025-06-01)

Evaluation of Human β-defensin-3 Diagnostic Role in a Group of Iraqi Patients with Osteoporosis
by: Zahraa S. Hassan, et al.
Published: (2024-12-01)

Synovial Fluid Alpha-defensin Lateral Flow Assay is Specific but Not Sensitive for Periprosthetic Joint Infection in Revision Arthroplasty: A Propensity Score-matched Analysis
by: Sze Hon Yu, et al.
Published: (2024-01-01)

BLOOD CONTENTS OF DEFENSINS IN PATIENTS WITH PNEUMONIAS CAUSED BY INFLUENZA А/H1N1
by: E. N. Romanova, et al.
Published: (2014-07-01)

Insights into the Antimicrobial Mechanisms of a Scorpion Defensin on <i>Staphylococcus aureus</i> Using Transcriptomic and Proteomic Analyses
by: Xuhua Yang, et al.
Published: (2025-03-01)

Identification of the Plant Defensin (MsPDF) Gene Family in <i>Medicago sativa</i> and Analysis of Expression Patterns Under Abiotic Stress
by: Meiyan Guo, et al.
Published: (2025-04-01)

Multifacets in silico study of Plant Defensin 1.1 protein (PDF1.1) in Brassica rapa (turnip)
by: Qudsia Naz, et al.
Published: (2025-01-01)

Antibacterial activity improvement in a point mutant K45E of the pepper defensin J1-1
by: Gilberto Andrés Muñoz-Pérez, et al.
Published: (2024-10-01)

Human β-defensin-3gene expression in mucosa of ORL organs
by: E. V. Tyrnova, et al.
Published: (2022-07-01)

Effects of the Tobacco Defensin NaD1 Against Susceptible and Resistant Strains of <i>Candida albicans</i>
by: Olga V. Shevchenko, et al.
Published: (2024-12-01)

Expression profile of β-defensin genes and the effect of stocking density on them in Chinese alligator blood
by: LU Yao, et al.
Published: (2020-10-01)

Therapeutic Potential of Insect Defensin DLP4 Against <i>Staphylococcus hyicus</i>-Infected Piglet Exudative Epidermitis
by: Xuanxuan Ma, et al.
Published: (2024-10-01)

Dental Visiting Patterns and Their Associations With Dental Caries and Periodontal Diseases
by: Najith Amarasena, et al.
Published: (2025-02-01)

Human beta defensin-2 protects the epithelial barrier during methicillin-resistant Staphylococcus aureus infection in chronic rhinosinusitis with nasal polyps
by: Tengfei Tian, et al.
Published: (2025-05-01)

Characterization of Plant Defensin (<i>PDF</i>) Genes in Banana (<i>Musa acuminata</i>) Reveals the Antifungal Ability of MaPDF2.2 to Fusarium Wilt Pathogens
by: Ruide Li, et al.
Published: (2025-05-01)

Results of the intraoperative alpha defensin lateral flow test in the second stage of revision hip arthroplasty
by: Valery Yu. Murylev, et al.
Published: (2024-12-01)

AhR‐Dependent Induction of β‐Defensin 1 in Colonic Epithelial Cells Regulates Cross‐Talk between Gut Microbiota and Immune Response Leading to Attenuation of Colitis
by: Manikandan Palrasu, et al.
Published: (2025-07-01)

Salivary microbiota profile in adult and children population according to active dentin caries: a metagenomic preliminary analysis
by: Nuria Tamayo-Estebaranz, et al.
Published: (2025-07-01)

Mapping Review of the Correlations Between Periodontitis, Dental Caries, and Endocarditis
by: Mario Dioguardi, et al.
Published: (2025-05-01)

Effects of the <i>DEFB1-20G>A</i> and <i>DEFB1-52G>A</i> gene polymorphism on the level of beta 1 defensin (DEFB1) in young adults with community-acquired pneumonias
by: B. T. Zagalaev, et al.
Published: (2025-01-01)

An Emulation Model Combining Caries and Periodontitis Risk Assessment With Student Performance Report: An Exploratory Project
by: David Johnsen, et al.
Published: (2025-06-01)

Heat-Killed <i>Lactobacillus paracasei</i> SMB092 Reduces Halitosis by Stimulating the Expression of β-Defensins in Oral Keratinocytes
by: Won-Ju Kim, et al.
Published: (2024-10-01)

An Evaluation of The Effect of Passive Smoking on Caries and Periodontal Index in Preschool Children
by: Uğur Akdağ, et al.
Published: (2024-10-01)

The role of human β-defensin 2 (HbD-2) and cathelicidin (LL-37) in the local protection of the upper respiratory tract in children with allergic rhinitis and bronchial asthma
by: Yu.K. Bolbot, et al.
Published: (2021-03-01)

The impact of vitamin D deficiency on caries, periodontitis, and oral cancer: A systematic review
by: A.S. Hussein, et al.
Published: (2024-07-01)