De novo non-canonical nanopore basecalling enables private communication using heavily-modified DNA data at single-molecule level
Abstract Hidden messages in DNA molecules by employing chemical modifications has been suggested for private data storage and transmission at high information density. However, rapidly decoding these “molecular keys” with corresponding basecallers remains challenging. We present DeepSME, a nanopore...
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| Main Authors: | Qingyuan Fan, Xuyang Zhao, Junyao Li, Ronghui Liu, Ming Liu, Qishun Feng, Yanping Long, Yang Fu, Jixian Zhai, Qing Pan, Yi Li |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-05-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-025-59357-2 |
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