Myxomatous degeneration of aortic valve causing severe aortic regurgitation. A rare case report

Myxomatous degeneration of a valve is a non-inflammatory degenerative process due to the disruption of the fibrous layer of the valve with mucopolysaccharide accumulation. It is mostly seen in the mitral valve but involvement in only aortic valve is rare. Here we present a case report of a 37-year-o...

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Main Authors: Rakesh Kumar Kodakkandla, Venkata Sreedatta Sarraju, Nagesh Ayalasomayajula
Format: Article
Language:English
Published: SAGE Publishing 2025-01-01
Series:SAGE Open Medical Case Reports
Online Access:https://doi.org/10.1177/2050313X251316992
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author Rakesh Kumar Kodakkandla
Venkata Sreedatta Sarraju
Nagesh Ayalasomayajula
author_facet Rakesh Kumar Kodakkandla
Venkata Sreedatta Sarraju
Nagesh Ayalasomayajula
author_sort Rakesh Kumar Kodakkandla
collection DOAJ
description Myxomatous degeneration of a valve is a non-inflammatory degenerative process due to the disruption of the fibrous layer of the valve with mucopolysaccharide accumulation. It is mostly seen in the mitral valve but involvement in only aortic valve is rare. Here we present a case report of a 37-year-old man who came with shortness of breath for the past three months and was diagnosed with severe aortic regurgitation due to myxomatous aortic valve causing rupture of the non-coronary and right coronary cusp. After preoperative workup, he was taken for aortic valve replacement surgery. Intraoperative findings confirmed the rupture of right and non-coronary cusps from their annular attachment and the myxomatous nature of the aortic valve. Histopathological examination confirmed the myxomatous changes in the valve. The patient underwent aortic valve replacement with a 23 mm TTK Chitra valve and on follow-up, he is doing well. Although aortic valve regurgitation is a common disease, myxomatous degeneration of isolated aortic valve leading to aortic regurgitation is rare. This patient did not have any signs of connective tissue disorders like Marfan’s syndrome, Ehlers-Danlos, etc., but presented with myxomatous aortic valve throwing an insight into further research into this rare disease.
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spelling doaj-art-69a1afae24de4e1b8b8aae428ba4cdf42025-01-30T16:04:03ZengSAGE PublishingSAGE Open Medical Case Reports2050-313X2025-01-011310.1177/2050313X251316992Myxomatous degeneration of aortic valve causing severe aortic regurgitation. A rare case reportRakesh Kumar KodakkandlaVenkata Sreedatta SarrajuNagesh AyalasomayajulaMyxomatous degeneration of a valve is a non-inflammatory degenerative process due to the disruption of the fibrous layer of the valve with mucopolysaccharide accumulation. It is mostly seen in the mitral valve but involvement in only aortic valve is rare. Here we present a case report of a 37-year-old man who came with shortness of breath for the past three months and was diagnosed with severe aortic regurgitation due to myxomatous aortic valve causing rupture of the non-coronary and right coronary cusp. After preoperative workup, he was taken for aortic valve replacement surgery. Intraoperative findings confirmed the rupture of right and non-coronary cusps from their annular attachment and the myxomatous nature of the aortic valve. Histopathological examination confirmed the myxomatous changes in the valve. The patient underwent aortic valve replacement with a 23 mm TTK Chitra valve and on follow-up, he is doing well. Although aortic valve regurgitation is a common disease, myxomatous degeneration of isolated aortic valve leading to aortic regurgitation is rare. This patient did not have any signs of connective tissue disorders like Marfan’s syndrome, Ehlers-Danlos, etc., but presented with myxomatous aortic valve throwing an insight into further research into this rare disease.https://doi.org/10.1177/2050313X251316992
spellingShingle Rakesh Kumar Kodakkandla
Venkata Sreedatta Sarraju
Nagesh Ayalasomayajula
Myxomatous degeneration of aortic valve causing severe aortic regurgitation. A rare case report
SAGE Open Medical Case Reports
title Myxomatous degeneration of aortic valve causing severe aortic regurgitation. A rare case report
title_full Myxomatous degeneration of aortic valve causing severe aortic regurgitation. A rare case report
title_fullStr Myxomatous degeneration of aortic valve causing severe aortic regurgitation. A rare case report
title_full_unstemmed Myxomatous degeneration of aortic valve causing severe aortic regurgitation. A rare case report
title_short Myxomatous degeneration of aortic valve causing severe aortic regurgitation. A rare case report
title_sort myxomatous degeneration of aortic valve causing severe aortic regurgitation a rare case report
url https://doi.org/10.1177/2050313X251316992
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