Classification and Differential Diagnosis of Diabetic Nephropathy
Diabetic nephropathy (DN) is a major cause of end-stage renal disease throughout the world in both developed and developing countries. This review briefly introduces the characteristic pathological changes of DN and Tervaert pathological classification, which divides DN into four classifications acc...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2017-01-01
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| Series: | Journal of Diabetes Research |
| Online Access: | http://dx.doi.org/10.1155/2017/8637138 |
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| _version_ | 1832561061569495040 |
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| author | Chenyang Qi Xing Mao Zhigang Zhang Huijuan Wu |
| author_facet | Chenyang Qi Xing Mao Zhigang Zhang Huijuan Wu |
| author_sort | Chenyang Qi |
| collection | DOAJ |
| description | Diabetic nephropathy (DN) is a major cause of end-stage renal disease throughout the world in both developed and developing countries. This review briefly introduces the characteristic pathological changes of DN and Tervaert pathological classification, which divides DN into four classifications according to glomerular lesions, along with a separate scoring system for tubular, interstitial, and vascular lesions. Given the heterogeneity of the renal lesions and the complex mechanism underlying diabetic nephropathy, Tervaert classification has both significance and controversies in the guidance of diagnosis and prognosis. Applications and evaluations using Tervaert classification and indications for renal biopsy are summarized in this review according to recent studies. Meanwhile, differential diagnosis with another nodular glomerulopathy and the situation that a typical DN superimposed with a nondiabetic renal disease (NDRD) are discussed and concluded in this review. |
| format | Article |
| id | doaj-art-6997633c3bfd4252b53ec60cf15ec515 |
| institution | Kabale University |
| issn | 2314-6745 2314-6753 |
| language | English |
| publishDate | 2017-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Diabetes Research |
| spelling | doaj-art-6997633c3bfd4252b53ec60cf15ec5152025-02-03T01:26:01ZengWileyJournal of Diabetes Research2314-67452314-67532017-01-01201710.1155/2017/86371388637138Classification and Differential Diagnosis of Diabetic NephropathyChenyang Qi0Xing Mao1Zhigang Zhang2Huijuan Wu3Department of Pathology, Shanghai Medical College, Fudan University, Shanghai, ChinaDepartment of Pathology, Shanghai Medical College, Fudan University, Shanghai, ChinaDepartment of Pathology, Shanghai Medical College, Fudan University, Shanghai, ChinaDepartment of Pathology, Shanghai Medical College, Fudan University, Shanghai, ChinaDiabetic nephropathy (DN) is a major cause of end-stage renal disease throughout the world in both developed and developing countries. This review briefly introduces the characteristic pathological changes of DN and Tervaert pathological classification, which divides DN into four classifications according to glomerular lesions, along with a separate scoring system for tubular, interstitial, and vascular lesions. Given the heterogeneity of the renal lesions and the complex mechanism underlying diabetic nephropathy, Tervaert classification has both significance and controversies in the guidance of diagnosis and prognosis. Applications and evaluations using Tervaert classification and indications for renal biopsy are summarized in this review according to recent studies. Meanwhile, differential diagnosis with another nodular glomerulopathy and the situation that a typical DN superimposed with a nondiabetic renal disease (NDRD) are discussed and concluded in this review.http://dx.doi.org/10.1155/2017/8637138 |
| spellingShingle | Chenyang Qi Xing Mao Zhigang Zhang Huijuan Wu Classification and Differential Diagnosis of Diabetic Nephropathy Journal of Diabetes Research |
| title | Classification and Differential Diagnosis of Diabetic Nephropathy |
| title_full | Classification and Differential Diagnosis of Diabetic Nephropathy |
| title_fullStr | Classification and Differential Diagnosis of Diabetic Nephropathy |
| title_full_unstemmed | Classification and Differential Diagnosis of Diabetic Nephropathy |
| title_short | Classification and Differential Diagnosis of Diabetic Nephropathy |
| title_sort | classification and differential diagnosis of diabetic nephropathy |
| url | http://dx.doi.org/10.1155/2017/8637138 |
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