Hybrid models of cell and tissue dynamics in tumor growth
Hybrid models of tumor growth, in which some regions are described at the celllevel and others at the continuum level, provide a flexible description thatallows alterations of cell-level properties and detailed descriptions of theinteraction with the tumor environment, yet retain the computational a...
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Format: | Article |
Language: | English |
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AIMS Press
2015-07-01
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Series: | Mathematical Biosciences and Engineering |
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Online Access: | https://www.aimspress.com/article/doi/10.3934/mbe.2015.12.1141 |
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author | Yangjin Kim Hans G. Othmer |
author_facet | Yangjin Kim Hans G. Othmer |
author_sort | Yangjin Kim |
collection | DOAJ |
description | Hybrid models of tumor growth, in which some regions are described at the celllevel and others at the continuum level, provide a flexible description thatallows alterations of cell-level properties and detailed descriptions of theinteraction with the tumor environment, yet retain the computational advantagesof continuum models where appropriate. We review aspects of the general approachand discuss applications to breast cancer and glioblastoma. |
format | Article |
id | doaj-art-698a963e4a5449ec9b17cd2117e57b97 |
institution | Kabale University |
issn | 1551-0018 |
language | English |
publishDate | 2015-07-01 |
publisher | AIMS Press |
record_format | Article |
series | Mathematical Biosciences and Engineering |
spelling | doaj-art-698a963e4a5449ec9b17cd2117e57b972025-01-24T02:33:57ZengAIMS PressMathematical Biosciences and Engineering1551-00182015-07-011261141115610.3934/mbe.2015.12.1141Hybrid models of cell and tissue dynamics in tumor growthYangjin Kim0Hans G. Othmer1Department of Mathematics, Konkuk University, SeoulSchool of Mathematics, University of Minnesota, Minneapolis, MN 55445Hybrid models of tumor growth, in which some regions are described at the celllevel and others at the continuum level, provide a flexible description thatallows alterations of cell-level properties and detailed descriptions of theinteraction with the tumor environment, yet retain the computational advantagesof continuum models where appropriate. We review aspects of the general approachand discuss applications to breast cancer and glioblastoma.https://www.aimspress.com/article/doi/10.3934/mbe.2015.12.1141microenvironment.tumor growthcancer |
spellingShingle | Yangjin Kim Hans G. Othmer Hybrid models of cell and tissue dynamics in tumor growth Mathematical Biosciences and Engineering microenvironment. tumor growth cancer |
title | Hybrid models of cell and tissue dynamics in tumor growth |
title_full | Hybrid models of cell and tissue dynamics in tumor growth |
title_fullStr | Hybrid models of cell and tissue dynamics in tumor growth |
title_full_unstemmed | Hybrid models of cell and tissue dynamics in tumor growth |
title_short | Hybrid models of cell and tissue dynamics in tumor growth |
title_sort | hybrid models of cell and tissue dynamics in tumor growth |
topic | microenvironment. tumor growth cancer |
url | https://www.aimspress.com/article/doi/10.3934/mbe.2015.12.1141 |
work_keys_str_mv | AT yangjinkim hybridmodelsofcellandtissuedynamicsintumorgrowth AT hansgothmer hybridmodelsofcellandtissuedynamicsintumorgrowth |