Pathological effects of pregabalin toxicity in rats

Abstract Background: Pregabalin (PGB) is one kind of gabapentinoid. The main mechanism of action is binding at the alpha-2-delta site, which inhibits calcium influx in response to depolarization at nerve terminals and, in turn, suppresses the release of glutamate, noradrenaline, and substance P. Obj...

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Bibliographic Details
Main Authors: Roaa Salih Mahdi, Nawras Najah, Sura Salman Ejam
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2024-01-01
Series:Medical Journal of Babylon
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Online Access:https://doi.org/10.4103/MJBL.MJBL_1709_23
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