Pathological effects of pregabalin toxicity in rats
Abstract Background: Pregabalin (PGB) is one kind of gabapentinoid. The main mechanism of action is binding at the alpha-2-delta site, which inhibits calcium influx in response to depolarization at nerve terminals and, in turn, suppresses the release of glutamate, noradrenaline, and substance P. Obj...
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Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Wolters Kluwer Medknow Publications
2024-01-01
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Series: | Medical Journal of Babylon |
Subjects: | |
Online Access: | https://doi.org/10.4103/MJBL.MJBL_1709_23 |
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