PSYCHEDELICS: CLINICAL EVIDENCE AND THERAPEUTIC MECHANISMS IN PSYCHIATRY

ABSTRACT Interest and academic research on psychedelics and psychedelic-assisted therapy in the treatment of psychiatric disorders has increased dramatically in the past two decades. In many ways, psychedelics represent a new therapeutic paradigm in the context of medicine. A key feature of psych...

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Main Author: JANI KAJANOJA, OSKARI KANTONEN, JUUSO KÄHÖNEN
Format: Article
Language:English
Published: The Finnish Foundation for Psychiatric Research 2024-11-01
Series:Psychiatria Fennica
Subjects:
Online Access:https://www.psykiatriantutkimussaatio.fi/wp-content/uploads/2024/10/Psychiatria_Fennica%E2%94%ACa2024_Kajanoja_et_al.pdf
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author JANI KAJANOJA, OSKARI KANTONEN, JUUSO KÄHÖNEN
author_facet JANI KAJANOJA, OSKARI KANTONEN, JUUSO KÄHÖNEN
author_sort JANI KAJANOJA, OSKARI KANTONEN, JUUSO KÄHÖNEN
collection DOAJ
description ABSTRACT Interest and academic research on psychedelics and psychedelic-assisted therapy in the treatment of psychiatric disorders has increased dramatically in the past two decades. In many ways, psychedelics represent a new therapeutic paradigm in the context of medicine. A key feature of psychedelics is their ability to reliably induce an altered experiential state, which is often described as mystical-like, self-transcending and meaningful, while also often experienced as challenging and anxietyprovoking. The subjective quality and content of the psychedelic experience has been consistently linked to their therapeutic effects. Here we review current understanding of the psychological and neurobiological mechanisms of psychedelics, as well as evidence of psychedelic-assisted therapy in the treatment of psychiatric conditions.
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issn 2489-6152
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spelling doaj-art-6955dfa019164387aa77a5268a7fda0f2025-01-22T08:52:45ZengThe Finnish Foundation for Psychiatric ResearchPsychiatria Fennica2489-61522024-11-0155140155PSYCHEDELICS: CLINICAL EVIDENCE AND THERAPEUTIC MECHANISMS IN PSYCHIATRYJANI KAJANOJA, OSKARI KANTONEN, JUUSO KÄHÖNENABSTRACT Interest and academic research on psychedelics and psychedelic-assisted therapy in the treatment of psychiatric disorders has increased dramatically in the past two decades. In many ways, psychedelics represent a new therapeutic paradigm in the context of medicine. A key feature of psychedelics is their ability to reliably induce an altered experiential state, which is often described as mystical-like, self-transcending and meaningful, while also often experienced as challenging and anxietyprovoking. The subjective quality and content of the psychedelic experience has been consistently linked to their therapeutic effects. Here we review current understanding of the psychological and neurobiological mechanisms of psychedelics, as well as evidence of psychedelic-assisted therapy in the treatment of psychiatric conditions.https://www.psykiatriantutkimussaatio.fi/wp-content/uploads/2024/10/Psychiatria_Fennica%E2%94%ACa2024_Kajanoja_et_al.pdfpsychedelicspsychedelic-assisted therapypsychopharmacologydepression
spellingShingle JANI KAJANOJA, OSKARI KANTONEN, JUUSO KÄHÖNEN
PSYCHEDELICS: CLINICAL EVIDENCE AND THERAPEUTIC MECHANISMS IN PSYCHIATRY
Psychiatria Fennica
psychedelics
psychedelic-assisted therapy
psychopharmacology
depression
title PSYCHEDELICS: CLINICAL EVIDENCE AND THERAPEUTIC MECHANISMS IN PSYCHIATRY
title_full PSYCHEDELICS: CLINICAL EVIDENCE AND THERAPEUTIC MECHANISMS IN PSYCHIATRY
title_fullStr PSYCHEDELICS: CLINICAL EVIDENCE AND THERAPEUTIC MECHANISMS IN PSYCHIATRY
title_full_unstemmed PSYCHEDELICS: CLINICAL EVIDENCE AND THERAPEUTIC MECHANISMS IN PSYCHIATRY
title_short PSYCHEDELICS: CLINICAL EVIDENCE AND THERAPEUTIC MECHANISMS IN PSYCHIATRY
title_sort psychedelics clinical evidence and therapeutic mechanisms in psychiatry
topic psychedelics
psychedelic-assisted therapy
psychopharmacology
depression
url https://www.psykiatriantutkimussaatio.fi/wp-content/uploads/2024/10/Psychiatria_Fennica%E2%94%ACa2024_Kajanoja_et_al.pdf
work_keys_str_mv AT janikajanojaoskarikantonenjuusokahonen psychedelicsclinicalevidenceandtherapeuticmechanismsinpsychiatry