PSYCHEDELICS: CLINICAL EVIDENCE AND THERAPEUTIC MECHANISMS IN PSYCHIATRY

ABSTRACT Interest and academic research on psychedelics and psychedelic-assisted therapy in the treatment of psychiatric disorders has increased dramatically in the past two decades. In many ways, psychedelics represent a new therapeutic paradigm in the context of medicine. A key feature of psych...

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Bibliographic Details
Main Author: JANI KAJANOJA, OSKARI KANTONEN, JUUSO KÄHÖNEN
Format: Article
Language:English
Published: The Finnish Foundation for Psychiatric Research 2024-11-01
Series:Psychiatria Fennica
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Online Access:https://www.psykiatriantutkimussaatio.fi/wp-content/uploads/2024/10/Psychiatria_Fennica%E2%94%ACa2024_Kajanoja_et_al.pdf
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Summary:ABSTRACT Interest and academic research on psychedelics and psychedelic-assisted therapy in the treatment of psychiatric disorders has increased dramatically in the past two decades. In many ways, psychedelics represent a new therapeutic paradigm in the context of medicine. A key feature of psychedelics is their ability to reliably induce an altered experiential state, which is often described as mystical-like, self-transcending and meaningful, while also often experienced as challenging and anxietyprovoking. The subjective quality and content of the psychedelic experience has been consistently linked to their therapeutic effects. Here we review current understanding of the psychological and neurobiological mechanisms of psychedelics, as well as evidence of psychedelic-assisted therapy in the treatment of psychiatric conditions.
ISSN:2489-6152