Chronic obstructive pulmonary disease and heart failure in real life: the tip of the iceberg in the sea of comorbidities. A prospective observational study
Chronic obstructive pulmonary disease (COPD) and heart failure (HF) are two of the most common conditions treated in internal medicine. Although it is known that these diseases often coexist, the specific characteristics of the affected patients and the prognostic implications are not yet well unde...
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PAGEPress Publications
2025-02-01
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| Series: | Monaldi Archives for Chest Disease |
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| Online Access: | https://www.monaldi-archives.org/macd/article/view/3157 |
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| author | Ombretta Para Marco Vanetti Chiara Dibonaventura Davide Salerno Lorenzo Caruso Christian Carleo Asim Raza Carlo Nozzoli Antonio Spanevello |
| author_facet | Ombretta Para Marco Vanetti Chiara Dibonaventura Davide Salerno Lorenzo Caruso Christian Carleo Asim Raza Carlo Nozzoli Antonio Spanevello |
| author_sort | Ombretta Para |
| collection | DOAJ |
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Chronic obstructive pulmonary disease (COPD) and heart failure (HF) are two of the most common conditions treated in internal medicine. Although it is known that these diseases often coexist, the specific characteristics of the affected patients and the prognostic implications are not yet well understood. Managing patients with both COPD and HF requires an integrated treatment approach. The aim of the study was to examine the association between COPD and HF. We conducted a prospective observational cohort study. All consenting patients admitted to the Internal Medicine Department from the Emergency Department with known or strongly suspected COPD were enrolled. A total of 144 patients were included, with 47.2% of them also having HF, distributed among the various HF subcategories as follows: 10.4% with HF with reduced ejection fraction (HFrEF), 3.5% with HF with mild-reduced ejection fraction, and 33.3% with HF with preserved ejection fraction (HFpEF). This result is consistent with the literature, which suggests a higher prevalence of COPD in patients with HFpEF compared to HFrEF. A Doppler echocardiography was performed during hospitalization. Some variables showed a statistically significant difference when comparing patients with COPD and HF to those with COPD without HF. Interestingly, the follow-up at 3 and 6 months post-discharge revealed higher mortality in patients with HF, with an odds ratio (95% confidence interval) of 10.0 (1.2-82.2). This study could contribute to a better understanding of the prognostic implications arising from the coexistence of COPD and HF, emphasizing the importance of a patient-centered approach in managing multiple comorbidities.
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| format | Article |
| id | doaj-art-6923d460e6e74d2c9f9fdeb1ea7d53a5 |
| institution | Kabale University |
| issn | 1122-0643 2532-5264 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | PAGEPress Publications |
| record_format | Article |
| series | Monaldi Archives for Chest Disease |
| spelling | doaj-art-6923d460e6e74d2c9f9fdeb1ea7d53a52025-02-05T01:40:05ZengPAGEPress PublicationsMonaldi Archives for Chest Disease1122-06432532-52642025-02-0110.4081/monaldi.2025.3157Chronic obstructive pulmonary disease and heart failure in real life: the tip of the iceberg in the sea of comorbidities. A prospective observational studyOmbretta Para0Marco Vanetti1https://orcid.org/0009-0007-3782-5021Chiara Dibonaventura2Davide Salerno3https://orcid.org/0009-0004-2805-0955Lorenzo Caruso4Christian Carleo5Asim Raza6https://orcid.org/0009-0008-9114-0637Carlo Nozzoli7Antonio Spanevello8PhD Research Program in “Clinical and Experimental Medicine and Medical Humanities”, University of Insubria, Varese; Internal Medicine 1, University Hospital of Careggi, FlorenceRespiratory Rehabilitation of the Institute of Tradate, Istituti Clinici Scientifici Maugeri IRCCS, Varese; Department of Medicine and Surgery, University of Insubria, VareseInternal Medicine 1, University Hospital of Careggi, FlorenceInternal Medicine 1, University Hospital of Careggi, FlorenceInternal Medicine 1, University Hospital of Careggi, FlorenceInternal Medicine 1, University Hospital of Careggi, FlorenceInternal Medicine 1, University Hospital of Careggi, FlorenceInternal Medicine 1, University Hospital of Careggi, FlorenceRespiratory Rehabilitation of the Institute of Tradate, Istituti Clinici Scientifici Maugeri IRCCS, Varese; Department of Medicine and Surgery, University of Insubria, Varese Chronic obstructive pulmonary disease (COPD) and heart failure (HF) are two of the most common conditions treated in internal medicine. Although it is known that these diseases often coexist, the specific characteristics of the affected patients and the prognostic implications are not yet well understood. Managing patients with both COPD and HF requires an integrated treatment approach. The aim of the study was to examine the association between COPD and HF. We conducted a prospective observational cohort study. All consenting patients admitted to the Internal Medicine Department from the Emergency Department with known or strongly suspected COPD were enrolled. A total of 144 patients were included, with 47.2% of them also having HF, distributed among the various HF subcategories as follows: 10.4% with HF with reduced ejection fraction (HFrEF), 3.5% with HF with mild-reduced ejection fraction, and 33.3% with HF with preserved ejection fraction (HFpEF). This result is consistent with the literature, which suggests a higher prevalence of COPD in patients with HFpEF compared to HFrEF. A Doppler echocardiography was performed during hospitalization. Some variables showed a statistically significant difference when comparing patients with COPD and HF to those with COPD without HF. Interestingly, the follow-up at 3 and 6 months post-discharge revealed higher mortality in patients with HF, with an odds ratio (95% confidence interval) of 10.0 (1.2-82.2). This study could contribute to a better understanding of the prognostic implications arising from the coexistence of COPD and HF, emphasizing the importance of a patient-centered approach in managing multiple comorbidities. https://www.monaldi-archives.org/macd/article/view/3157Heart failureCOPDbronchitisejection fractioncomorbidities |
| spellingShingle | Ombretta Para Marco Vanetti Chiara Dibonaventura Davide Salerno Lorenzo Caruso Christian Carleo Asim Raza Carlo Nozzoli Antonio Spanevello Chronic obstructive pulmonary disease and heart failure in real life: the tip of the iceberg in the sea of comorbidities. A prospective observational study Monaldi Archives for Chest Disease Heart failure COPD bronchitis ejection fraction comorbidities |
| title | Chronic obstructive pulmonary disease and heart failure in real life: the tip of the iceberg in the sea of comorbidities. A prospective observational study |
| title_full | Chronic obstructive pulmonary disease and heart failure in real life: the tip of the iceberg in the sea of comorbidities. A prospective observational study |
| title_fullStr | Chronic obstructive pulmonary disease and heart failure in real life: the tip of the iceberg in the sea of comorbidities. A prospective observational study |
| title_full_unstemmed | Chronic obstructive pulmonary disease and heart failure in real life: the tip of the iceberg in the sea of comorbidities. A prospective observational study |
| title_short | Chronic obstructive pulmonary disease and heart failure in real life: the tip of the iceberg in the sea of comorbidities. A prospective observational study |
| title_sort | chronic obstructive pulmonary disease and heart failure in real life the tip of the iceberg in the sea of comorbidities a prospective observational study |
| topic | Heart failure COPD bronchitis ejection fraction comorbidities |
| url | https://www.monaldi-archives.org/macd/article/view/3157 |
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