Seroprevalence of Antibodies against Human Herpesvirus 6 in the Quebec City Area

Seroprevalence of antibodies against human herpesvirus 6 was determined in a sample of 303 randomly selected individuals from the Quebec City area. The influence of different variables on antibody litres was also evaluated. Human herpesvirus 6 was grown in the HSB-2 cell line, and antibody litres we...

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Main Authors: Louise Deschênes, Jean R Joly, Michel Couillard, Gilles Richer
Format: Article
Language:English
Published: Wiley 1992-01-01
Series:Canadian Journal of Infectious Diseases
Online Access:http://dx.doi.org/10.1155/1992/837029
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author Louise Deschênes
Jean R Joly
Michel Couillard
Gilles Richer
author_facet Louise Deschênes
Jean R Joly
Michel Couillard
Gilles Richer
author_sort Louise Deschênes
collection DOAJ
description Seroprevalence of antibodies against human herpesvirus 6 was determined in a sample of 303 randomly selected individuals from the Quebec City area. The influence of different variables on antibody litres was also evaluated. Human herpesvirus 6 was grown in the HSB-2 cell line, and antibody litres were measured by indirect immunofluorescence. Serum samples were collected from 177 females and 126 males ranging in age from two months to 88 years. Ninety-nine per cent (300 of 303) of this population had an antibody titre of at least 1:10, whereas 75% had a titre of at least 1:80. Women had a higher geometric mean litre than men (P=0.06). This difference between sexes varied according to age and became statistically significant in subjects older than 20 years of age (P=0.04). It was found that this difference was attributable to higher antibody litres in women in the 15 to 40 year age group who had previously had children.
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spelling doaj-art-69191d1459f645b5be8537f64e6e37f42025-02-03T05:54:09ZengWileyCanadian Journal of Infectious Diseases1180-23321992-01-013417918410.1155/1992/837029Seroprevalence of Antibodies against Human Herpesvirus 6 in the Quebec City AreaLouise Deschênes0Jean R Joly1Michel Couillard2Gilles Richer3Laboratoire de virologie. Département de microbiologie, Faculté de médecine, Université Laval, Sainte-Foy, Québec, CanadaLaboratoire de virologie. Département de microbiologie, Faculté de médecine, Université Laval, Sainte-Foy, Québec, CanadaLaboratoire de virologie. Département de microbiologie, Faculté de médecine, Université Laval, Sainte-Foy, Québec, CanadaLaboratoire de virologie. Département de microbiologie, Faculté de médecine, Université Laval, Sainte-Foy, Québec, CanadaSeroprevalence of antibodies against human herpesvirus 6 was determined in a sample of 303 randomly selected individuals from the Quebec City area. The influence of different variables on antibody litres was also evaluated. Human herpesvirus 6 was grown in the HSB-2 cell line, and antibody litres were measured by indirect immunofluorescence. Serum samples were collected from 177 females and 126 males ranging in age from two months to 88 years. Ninety-nine per cent (300 of 303) of this population had an antibody titre of at least 1:10, whereas 75% had a titre of at least 1:80. Women had a higher geometric mean litre than men (P=0.06). This difference between sexes varied according to age and became statistically significant in subjects older than 20 years of age (P=0.04). It was found that this difference was attributable to higher antibody litres in women in the 15 to 40 year age group who had previously had children.http://dx.doi.org/10.1155/1992/837029
spellingShingle Louise Deschênes
Jean R Joly
Michel Couillard
Gilles Richer
Seroprevalence of Antibodies against Human Herpesvirus 6 in the Quebec City Area
Canadian Journal of Infectious Diseases
title Seroprevalence of Antibodies against Human Herpesvirus 6 in the Quebec City Area
title_full Seroprevalence of Antibodies against Human Herpesvirus 6 in the Quebec City Area
title_fullStr Seroprevalence of Antibodies against Human Herpesvirus 6 in the Quebec City Area
title_full_unstemmed Seroprevalence of Antibodies against Human Herpesvirus 6 in the Quebec City Area
title_short Seroprevalence of Antibodies against Human Herpesvirus 6 in the Quebec City Area
title_sort seroprevalence of antibodies against human herpesvirus 6 in the quebec city area
url http://dx.doi.org/10.1155/1992/837029
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AT gillesricher seroprevalenceofantibodiesagainsthumanherpesvirus6inthequebeccityarea