Antithrombotic Dilemmas after Left Atrial Appendage Occlusion Watchman Device Placement
Antithrombotic therapy for stroke prevention in patients with atrial fibrillation (AF) has dramatically shifted from warfarin, a vitamin K antagonist, to the direct oral anticoagulants (DOACs) such as dabigatran, apixaban, and rivaroxaban. In patients with contraindications to oral anticoagulation,...
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| Format: | Article |
| Language: | English |
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Wiley
2019-01-01
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| Series: | Case Reports in Cardiology |
| Online Access: | http://dx.doi.org/10.1155/2019/5247105 |
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| author | Tania Ahuja Scarlett Murphy Daniel J. Sartori |
| author_facet | Tania Ahuja Scarlett Murphy Daniel J. Sartori |
| author_sort | Tania Ahuja |
| collection | DOAJ |
| description | Antithrombotic therapy for stroke prevention in patients with atrial fibrillation (AF) has dramatically shifted from warfarin, a vitamin K antagonist, to the direct oral anticoagulants (DOACs) such as dabigatran, apixaban, and rivaroxaban. In patients with contraindications to oral anticoagulation, left atrial appendage occlusion (LAAO) devices, such as the Watchman™ device, may be considered; however, temporary postimplantation antithrombotic therapy is still a recommended practice. We present a case of complex antithrombotic management, post LAAO device implantation, designed to avoid drug interactions with concomitant rifampin use and remained necessary secondary to subsequent device leak. This case highlights the challenges of antithrombotic therapy post LAAO device placement in a complex, but representative, patient. |
| format | Article |
| id | doaj-art-6905170626094bd6ba37355fc61587d1 |
| institution | Kabale University |
| issn | 2090-6404 2090-6412 |
| language | English |
| publishDate | 2019-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Cardiology |
| spelling | doaj-art-6905170626094bd6ba37355fc61587d12025-02-03T01:30:06ZengWileyCase Reports in Cardiology2090-64042090-64122019-01-01201910.1155/2019/52471055247105Antithrombotic Dilemmas after Left Atrial Appendage Occlusion Watchman Device PlacementTania Ahuja0Scarlett Murphy1Daniel J. Sartori2New York University Langone Health, Department of Pharmacy, 550 First Avenue, New York, NY 10016, USANew York University Langone Health, Department of Medicine, 550 First Avenue, New York, NY 10016, USANew York University Langone Health, Department of Medicine, 550 First Avenue, New York, NY 10016, USAAntithrombotic therapy for stroke prevention in patients with atrial fibrillation (AF) has dramatically shifted from warfarin, a vitamin K antagonist, to the direct oral anticoagulants (DOACs) such as dabigatran, apixaban, and rivaroxaban. In patients with contraindications to oral anticoagulation, left atrial appendage occlusion (LAAO) devices, such as the Watchman™ device, may be considered; however, temporary postimplantation antithrombotic therapy is still a recommended practice. We present a case of complex antithrombotic management, post LAAO device implantation, designed to avoid drug interactions with concomitant rifampin use and remained necessary secondary to subsequent device leak. This case highlights the challenges of antithrombotic therapy post LAAO device placement in a complex, but representative, patient.http://dx.doi.org/10.1155/2019/5247105 |
| spellingShingle | Tania Ahuja Scarlett Murphy Daniel J. Sartori Antithrombotic Dilemmas after Left Atrial Appendage Occlusion Watchman Device Placement Case Reports in Cardiology |
| title | Antithrombotic Dilemmas after Left Atrial Appendage Occlusion Watchman Device Placement |
| title_full | Antithrombotic Dilemmas after Left Atrial Appendage Occlusion Watchman Device Placement |
| title_fullStr | Antithrombotic Dilemmas after Left Atrial Appendage Occlusion Watchman Device Placement |
| title_full_unstemmed | Antithrombotic Dilemmas after Left Atrial Appendage Occlusion Watchman Device Placement |
| title_short | Antithrombotic Dilemmas after Left Atrial Appendage Occlusion Watchman Device Placement |
| title_sort | antithrombotic dilemmas after left atrial appendage occlusion watchman device placement |
| url | http://dx.doi.org/10.1155/2019/5247105 |
| work_keys_str_mv | AT taniaahuja antithromboticdilemmasafterleftatrialappendageocclusionwatchmandeviceplacement AT scarlettmurphy antithromboticdilemmasafterleftatrialappendageocclusionwatchmandeviceplacement AT danieljsartori antithromboticdilemmasafterleftatrialappendageocclusionwatchmandeviceplacement |