DCAF7 Acts as A Scaffold to Recruit USP10 for G3BP1 Deubiquitylation and Facilitates Chemoresistance and Metastasis in Nasopharyngeal Carcinoma

DCAF7 Acts as A Scaffold to Recruit USP10 for G3BP1 Deubiquitylation and Facilitates Chemoresistance and Metastasis in Nasopharyngeal Carcinoma

Abstract Despite docetaxel combined with cisplatin and 5‐fluorouracil (TPF) being the established treatment for advanced nasopharyngeal carcinoma (NPC), there are patients who do not respond positively to this form of therapy. However, the mechanisms underlying this lack of benefit remain unclear. D...

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Main Authors: Qing‐Jie Li, Xue‐Liang Fang, Ying‐Qin Li, Jia‐Yi Lin, Cheng‐Long Huang, Shi‐Wei He, Sheng‐Yan Huang, Jun‐Yan Li, Sha Gong, Na Liu, Jun Ma, Yin Zhao, Ling‐Long Tang
Format: Article
Language:English
Published: Wiley 2024-09-01
Series:Advanced Science
Subjects:
chemoresistance
chemotherapy
DCAF7
deubiquitylation
nasopharyngeal carcinoma
Online Access:https://doi.org/10.1002/advs.202403262
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