MSC-derived exosome ameliorates pulmonary fibrosis by modulating NOD 1/NLRP3-mediated epithelial-mesenchymal transition and inflammation
Background: Pulmonary fibrosis (PF) is an irreversible and usually fatal lung disease. In recent years, the therapeutic role of exosomes derived from mesenchymal stem cells (MSC-exos) in anti-fibrotic treatment has received much attention. In this study, we aimed to determine the anti-fibrotic prope...
Saved in:
Main Authors: | Wei Chen, Jie Peng, Xiangyi Tang, Shao Ouyang |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2025-01-01
|
Series: | Heliyon |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2405844024174671 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
MSC-exosomes pretreated by Danshensu extracts pretreating to target the hsa-miR-27a-5p and STAT3-SHANK2 to enhanced antifibrotic therapy
by: Jiabin Liang, et al.
Published: (2025-02-01) -
CXC chemokine receptor 7 ameliorates renal fibrosis by inhibiting β-catenin signaling and epithelial-to-mesenchymal transition in tubular epithelial cells
by: Ping Meng, et al.
Published: (2024-12-01) -
Optimizing therapeutic outcomes: preconditioning strategies for MSC-derived extracellular vesicles
by: Yuqi Song, et al.
Published: (2025-02-01) -
Myofibroblast-derived exosomes enhance macrophages to myofibroblasts transition and kidney fibrosis
by: Wenqiang Yu, et al.
Published: (2024-12-01) -
Bushen Huoxue formula protects against renal fibrosis and pyroptosis in chronic kidney disease by inhibiting ROS/NLRP3-mediated inflammasome activation
by: Lin Liao, et al.
Published: (2024-12-01)