Dose- and sex-dependent effects on umbilical cord-derived mesenchymal stem cell efficacy in regeneration of a full-thickness tendon defect in a rat model

Dose- and sex-dependent effects on umbilical cord-derived mesenchymal stem cell efficacy in regeneration of a full-thickness tendon defect in a rat model

Background Mesenchymal stem cells (MSCs) have shown potential in regenerative medicine. In the present study the effects of MSC dosage and recipient sex on tendon regeneration were evaluated. Methods A full-thickness tendon defect (FTTD) was created on supraspinatus tendons (SSTs) of rats and cryopr...

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Bibliographic Details
Main Authors: Ji-Hye Yea, Chris Hyunchul Jo
Format: Article
Language:English
Published: Korean Shoulder and Elbow Society 2025-02-01
Series:Clinics in Shoulder and Elbow
Subjects:
shoulder pain
tendon regeneration
mesenchymal stem cells
sex
dose
Online Access:http://cisejournal.org/upload/pdf/cise-2024-00626.pdf
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