Therapeutic administration of the chemokine CXCL1/KC abrogates autoimmune inflammatory heart disease.

Myocarditis, often due to an aberrant immune response to infection, is a major cause of dilated cardiomyopathy. Microbial pattern recognition receptors, such as TLRs, orchestrate the cytokine and chemokine responses that augment or limit the severity of myocarditis. Using the mouse model of experime...

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Bibliographic Details
Main Authors: Kurt Bachmaier, Sophie Toya, Asrar B Malik
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0089647&type=printable
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