Electrospun Nanostructured Fibers of Collagen-Biomimetic Apatite on Titanium Alloy
Titanium and its alloys are currently the mainly used materials to manufacture orthopaedic implants due to their excellent mechanical properties and corrosion resistance. Although these materials are bioinert, the improvement of biological properties (e.g., bone implant contact) can be obtained by t...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | Bioinorganic Chemistry and Applications |
| Online Access: | http://dx.doi.org/10.1155/2012/123953 |
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| author | Michele Iafisco Ismaela Foltran Simona Sabbatini Giorgio Tosi Norberto Roveri |
| author_facet | Michele Iafisco Ismaela Foltran Simona Sabbatini Giorgio Tosi Norberto Roveri |
| author_sort | Michele Iafisco |
| collection | DOAJ |
| description | Titanium and its alloys are currently the mainly used materials to manufacture orthopaedic implants due to their excellent mechanical properties and corrosion resistance. Although these materials are bioinert, the improvement of biological properties (e.g., bone implant contact) can be obtained by the application of a material that mimics the bone extracellular matrix. To this aim, this work describes a new method to produce nanostructured collagen-apatite composites on titanium alloy substrate, by combining electrospinning and biomimetic mineralization. The characterization results showed that the obtained mineralized scaffolds have morphological, structural, and chemical compositional features similar to natural bone extracellular matrix. Finally, the topographic distribution of the chemical composition in the mineralized matrix evaluated by Fourier Transform Infrared microspectroscopy demonstrated that the apatite nanocrystals cover the collagen fibers assembled by the electrospinning. |
| format | Article |
| id | doaj-art-68c0056ffe804e999edb93cc2798c30b |
| institution | Kabale University |
| issn | 1565-3633 1687-479X |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Bioinorganic Chemistry and Applications |
| spelling | doaj-art-68c0056ffe804e999edb93cc2798c30b2025-02-03T01:03:42ZengWileyBioinorganic Chemistry and Applications1565-36331687-479X2012-01-01201210.1155/2012/123953123953Electrospun Nanostructured Fibers of Collagen-Biomimetic Apatite on Titanium AlloyMichele Iafisco0Ismaela Foltran1Simona Sabbatini2Giorgio Tosi3Norberto Roveri4Dipartimento di Chimica “G. Ciamician,” Alma Mater Studiorum Università di Bologna, Via Selmi 2, 40126 Bologna, ItalyDipartimento di Chimica “G. Ciamician,” Alma Mater Studiorum Università di Bologna, Via Selmi 2, 40126 Bologna, ItalyDipartimento di Scienze e Tecnologie Chimiche, Università Politecnica delle Marche, Via Brecce Bianche, 60131 Ancona, ItalyDipartimento di Scienze e Tecnologie Chimiche, Università Politecnica delle Marche, Via Brecce Bianche, 60131 Ancona, ItalyDipartimento di Chimica “G. Ciamician,” Alma Mater Studiorum Università di Bologna, Via Selmi 2, 40126 Bologna, ItalyTitanium and its alloys are currently the mainly used materials to manufacture orthopaedic implants due to their excellent mechanical properties and corrosion resistance. Although these materials are bioinert, the improvement of biological properties (e.g., bone implant contact) can be obtained by the application of a material that mimics the bone extracellular matrix. To this aim, this work describes a new method to produce nanostructured collagen-apatite composites on titanium alloy substrate, by combining electrospinning and biomimetic mineralization. The characterization results showed that the obtained mineralized scaffolds have morphological, structural, and chemical compositional features similar to natural bone extracellular matrix. Finally, the topographic distribution of the chemical composition in the mineralized matrix evaluated by Fourier Transform Infrared microspectroscopy demonstrated that the apatite nanocrystals cover the collagen fibers assembled by the electrospinning.http://dx.doi.org/10.1155/2012/123953 |
| spellingShingle | Michele Iafisco Ismaela Foltran Simona Sabbatini Giorgio Tosi Norberto Roveri Electrospun Nanostructured Fibers of Collagen-Biomimetic Apatite on Titanium Alloy Bioinorganic Chemistry and Applications |
| title | Electrospun Nanostructured Fibers of Collagen-Biomimetic Apatite on Titanium Alloy |
| title_full | Electrospun Nanostructured Fibers of Collagen-Biomimetic Apatite on Titanium Alloy |
| title_fullStr | Electrospun Nanostructured Fibers of Collagen-Biomimetic Apatite on Titanium Alloy |
| title_full_unstemmed | Electrospun Nanostructured Fibers of Collagen-Biomimetic Apatite on Titanium Alloy |
| title_short | Electrospun Nanostructured Fibers of Collagen-Biomimetic Apatite on Titanium Alloy |
| title_sort | electrospun nanostructured fibers of collagen biomimetic apatite on titanium alloy |
| url | http://dx.doi.org/10.1155/2012/123953 |
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