A Reversible Cytotoxic Lesion of the Corpus Callosum Developing after a Rapid Alteration in Cerebrospinal Fluid Pressure/Volume in a Patient with New Daily Persistent Headache

A case is presented of a woman with a history of daily persistent head pressure and dizziness who developed a cytotoxic lesion of the splenium of the corpus callosum after an acute withdrawal of chronic acetazolamide treatment and then, in quick succession, a CSF pressure/volume drop with a lumbar p...

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Main Authors: Todd D. Rozen, Hector A. Robles
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Case Reports in Neurological Medicine
Online Access:http://dx.doi.org/10.1155/2020/8849645
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author Todd D. Rozen
Hector A. Robles
author_facet Todd D. Rozen
Hector A. Robles
author_sort Todd D. Rozen
collection DOAJ
description A case is presented of a woman with a history of daily persistent head pressure and dizziness who developed a cytotoxic lesion of the splenium of the corpus callosum after an acute withdrawal of chronic acetazolamide treatment and then, in quick succession, a CSF pressure/volume drop with a lumbar puncture. This is the first documentation that rapid alterations of CSF pressure/volume may trigger cytotoxic lesions in the central nervous system.
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spelling doaj-art-68b638a2af874230b5174b9def8023252025-02-03T01:28:08ZengWileyCase Reports in Neurological Medicine2090-66682090-66762020-01-01202010.1155/2020/88496458849645A Reversible Cytotoxic Lesion of the Corpus Callosum Developing after a Rapid Alteration in Cerebrospinal Fluid Pressure/Volume in a Patient with New Daily Persistent HeadacheTodd D. Rozen0Hector A. Robles1Department of Neurology and Neuroradiology, Mayo Clinic Florida, Jacksonville, USADepartment of Neurology and Neuroradiology, Mayo Clinic Florida, Jacksonville, USAA case is presented of a woman with a history of daily persistent head pressure and dizziness who developed a cytotoxic lesion of the splenium of the corpus callosum after an acute withdrawal of chronic acetazolamide treatment and then, in quick succession, a CSF pressure/volume drop with a lumbar puncture. This is the first documentation that rapid alterations of CSF pressure/volume may trigger cytotoxic lesions in the central nervous system.http://dx.doi.org/10.1155/2020/8849645
spellingShingle Todd D. Rozen
Hector A. Robles
A Reversible Cytotoxic Lesion of the Corpus Callosum Developing after a Rapid Alteration in Cerebrospinal Fluid Pressure/Volume in a Patient with New Daily Persistent Headache
Case Reports in Neurological Medicine
title A Reversible Cytotoxic Lesion of the Corpus Callosum Developing after a Rapid Alteration in Cerebrospinal Fluid Pressure/Volume in a Patient with New Daily Persistent Headache
title_full A Reversible Cytotoxic Lesion of the Corpus Callosum Developing after a Rapid Alteration in Cerebrospinal Fluid Pressure/Volume in a Patient with New Daily Persistent Headache
title_fullStr A Reversible Cytotoxic Lesion of the Corpus Callosum Developing after a Rapid Alteration in Cerebrospinal Fluid Pressure/Volume in a Patient with New Daily Persistent Headache
title_full_unstemmed A Reversible Cytotoxic Lesion of the Corpus Callosum Developing after a Rapid Alteration in Cerebrospinal Fluid Pressure/Volume in a Patient with New Daily Persistent Headache
title_short A Reversible Cytotoxic Lesion of the Corpus Callosum Developing after a Rapid Alteration in Cerebrospinal Fluid Pressure/Volume in a Patient with New Daily Persistent Headache
title_sort reversible cytotoxic lesion of the corpus callosum developing after a rapid alteration in cerebrospinal fluid pressure volume in a patient with new daily persistent headache
url http://dx.doi.org/10.1155/2020/8849645
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