Replication and Meta-Analysis of 13,000 Cases Defines the Risk for Interleukin-23 Receptor and Autophagy-Related 16-Like 1 Variants in Crohn’s Disease

Replication and Meta-Analysis of 13,000 Cases Defines the Risk for Interleukin-23 Receptor and Autophagy-Related 16-Like 1 Variants in Crohn’s Disease

BACKGROUND/OBJECTIVE: Variants in the interleukin-23 receptor (IL23R) and the autophagy-related 16-like 1 (ATG16L1) genes have been associated with an increased risk of Crohn’s disease (CD). Both genes were identified through genome-wide association scans and subsequent studies have validated these...

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Main Authors: Lynn Cotterill, Debbie Payne, Scott Levison, John McLaughlin, Emma Wesley, Mark Feeney, Hilary Durbin, Simon Lal, Alistair Makin, Simon Campbell, Stephen A Roberts, Catherine O’Neill, Cathryn Edwards, William G Newman
Format: Article
Language:English
Published: Wiley 2010-01-01
Series:Canadian Journal of Gastroenterology
Online Access:http://dx.doi.org/10.1155/2010/480458
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