Renal Sinus Lipomatosis in Transplanted Kidneys: An Unusual Clinical Case

Renal sinus lipomatosis (RSL) represents an abnormal proliferation of the adipose tissue surrounding the renal pelvis of uncertain origin, associated with aging, obesity, steroid excess, infections, and calculosis. It represents a rare complication in transplanted kidneys, and, despite the accurate...

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Main Authors: Luca Apicella, Gianfranco Vallone, Sossio Vitale, Gianluca Garofalo, Luigi Russo, Riccardo Gallo, Stefano Federico, Massimo Sabbatini
Format: Article
Language:English
Published: Wiley 2011-01-01
Series:Case Reports in Transplantation
Online Access:http://dx.doi.org/10.1155/2011/161759
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author Luca Apicella
Gianfranco Vallone
Sossio Vitale
Gianluca Garofalo
Luigi Russo
Riccardo Gallo
Stefano Federico
Massimo Sabbatini
author_facet Luca Apicella
Gianfranco Vallone
Sossio Vitale
Gianluca Garofalo
Luigi Russo
Riccardo Gallo
Stefano Federico
Massimo Sabbatini
author_sort Luca Apicella
collection DOAJ
description Renal sinus lipomatosis (RSL) represents an abnormal proliferation of the adipose tissue surrounding the renal pelvis of uncertain origin, associated with aging, obesity, steroid excess, infections, and calculosis. It represents a rare complication in transplanted kidneys, and, despite the accurate and prolonged radiological followup of transplanted organs, only a few cases of RSL have been described in graft recipients, with no remarkable effects on renal function. The diagnosis relies on ultrasonography (US), magnetic resonance imaging (MRI), computed tomography (CT), and, finally, percutaneous biopsy. We describe the case of an extensive RSL in a 38-year-old renal transplant recipient, diagnosed by ultrasonography and computed tomography. The patient underwent a radiologic study because of an acute, asymptomatic renal impairment, that led to the diagnosis of a RSL of unusual dimensions, associated with a discrete hydronephrosis. Paradoxically, after a short course of steroids, the recovery of renal function and the partial resolution of calyceal dilatation were observed. The rarity of this affection, the need of a differential diagnosis with fat-containing tumors, and the possibility of parenchymal inflammation associated with RSL, potentially responsive to steroids, are also discussed.
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spelling doaj-art-689163d6539e482f9b96f0784e980ada2025-02-03T01:12:12ZengWileyCase Reports in Transplantation2090-69432090-69512011-01-01201110.1155/2011/161759161759Renal Sinus Lipomatosis in Transplanted Kidneys: An Unusual Clinical CaseLuca Apicella0Gianfranco Vallone1Sossio Vitale2Gianluca Garofalo3Luigi Russo4Riccardo Gallo5Stefano Federico6Massimo Sabbatini7Nephrology and Renal Transplantation, Department of Systematic Pathology, University of Naples “Federico II”, 80131 Naples, ItalyDepartment of Radiology, University of Naples “Federico II”, Via S. Pansini 5, 80131 Naples, ItalyNephrology and Renal Transplantation, Department of Systematic Pathology, University of Naples “Federico II”, 80131 Naples, ItalyNephrology and Renal Transplantation, Department of Systematic Pathology, University of Naples “Federico II”, 80131 Naples, ItalyNephrology and Renal Transplantation, Department of Systematic Pathology, University of Naples “Federico II”, 80131 Naples, ItalyNephrology and Renal Transplantation, Department of Systematic Pathology, University of Naples “Federico II”, 80131 Naples, ItalyNephrology and Renal Transplantation, Department of Systematic Pathology, University of Naples “Federico II”, 80131 Naples, ItalyNephrology and Renal Transplantation, Department of Systematic Pathology, University of Naples “Federico II”, 80131 Naples, ItalyRenal sinus lipomatosis (RSL) represents an abnormal proliferation of the adipose tissue surrounding the renal pelvis of uncertain origin, associated with aging, obesity, steroid excess, infections, and calculosis. It represents a rare complication in transplanted kidneys, and, despite the accurate and prolonged radiological followup of transplanted organs, only a few cases of RSL have been described in graft recipients, with no remarkable effects on renal function. The diagnosis relies on ultrasonography (US), magnetic resonance imaging (MRI), computed tomography (CT), and, finally, percutaneous biopsy. We describe the case of an extensive RSL in a 38-year-old renal transplant recipient, diagnosed by ultrasonography and computed tomography. The patient underwent a radiologic study because of an acute, asymptomatic renal impairment, that led to the diagnosis of a RSL of unusual dimensions, associated with a discrete hydronephrosis. Paradoxically, after a short course of steroids, the recovery of renal function and the partial resolution of calyceal dilatation were observed. The rarity of this affection, the need of a differential diagnosis with fat-containing tumors, and the possibility of parenchymal inflammation associated with RSL, potentially responsive to steroids, are also discussed.http://dx.doi.org/10.1155/2011/161759
spellingShingle Luca Apicella
Gianfranco Vallone
Sossio Vitale
Gianluca Garofalo
Luigi Russo
Riccardo Gallo
Stefano Federico
Massimo Sabbatini
Renal Sinus Lipomatosis in Transplanted Kidneys: An Unusual Clinical Case
Case Reports in Transplantation
title Renal Sinus Lipomatosis in Transplanted Kidneys: An Unusual Clinical Case
title_full Renal Sinus Lipomatosis in Transplanted Kidneys: An Unusual Clinical Case
title_fullStr Renal Sinus Lipomatosis in Transplanted Kidneys: An Unusual Clinical Case
title_full_unstemmed Renal Sinus Lipomatosis in Transplanted Kidneys: An Unusual Clinical Case
title_short Renal Sinus Lipomatosis in Transplanted Kidneys: An Unusual Clinical Case
title_sort renal sinus lipomatosis in transplanted kidneys an unusual clinical case
url http://dx.doi.org/10.1155/2011/161759
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