GPR120/FFAR4 protects retinal vascular endothelial cells against high glucose injury via suppressing ROS-ERS mediated apoptosis

GPR120/FFAR4 protects retinal vascular endothelial cells against high glucose injury via suppressing ROS-ERS mediated apoptosis

AIM: To evaluate the role of reactive oxygen species-endoplasmic reticulum stress (ROS-ERS) in the cellular protection of G protein-coupled receptor 120 (GPR120/FFAR4) against high glucose (HG) induced human retinal vascular endothelial cell (HRVEC) injury and its underlying mechanisms. METHODS: HRV...

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Bibliographic Details
Main Authors: Li-Zhao Wang, Jie-Jing Yan
Format: Article
Language:English
Published: Press of International Journal of Ophthalmology (IJO PRESS) 2025-03-01
Series:International Journal of Ophthalmology
Subjects:
gpr120/ffar4
high glucose
apoptosis
oxidative stress
retinal vascular endothelial cells
Online Access:http://ies.ijo.cn/en_publish/2025/3/20250302.pdf
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http://ies.ijo.cn/en_publish/2025/3/20250302.pdf

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