Development and Formulation of the Experimental Dentifrice Based on Passiflora mollissima (Tumbo) with and without Fluoride Anion: Antibacterial Activity on Seven Antimicrobial Strains

Objectives. To develop and formulate a new experimental dentifrice with and without fluoride based on the peel and the fruit of the Passiflora mollissima (tumbo) and also to evaluate its antimicrobial activity against seven bacterial strains. Methods. The sample was calculated using the mean compari...

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Main Authors: Frank Mayta-Tovalino, Eloy Gamboa, Richard Sánchez, Jorge Rios, Ramín Medina, Martín García, Jhonn Asencios
Format: Article
Language:English
Published: Wiley 2019-01-01
Series:International Journal of Dentistry
Online Access:http://dx.doi.org/10.1155/2019/9056590
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author Frank Mayta-Tovalino
Eloy Gamboa
Richard Sánchez
Jorge Rios
Ramín Medina
Martín García
Jhonn Asencios
author_facet Frank Mayta-Tovalino
Eloy Gamboa
Richard Sánchez
Jorge Rios
Ramín Medina
Martín García
Jhonn Asencios
author_sort Frank Mayta-Tovalino
collection DOAJ
description Objectives. To develop and formulate a new experimental dentifrice with and without fluoride based on the peel and the fruit of the Passiflora mollissima (tumbo) and also to evaluate its antimicrobial activity against seven bacterial strains. Methods. The sample was calculated using the mean comparison formula, obtaining wells (n = 12) for each of the strains evaluated: S. mutans, E. faecalis, Actinomyces, Lactobacillus, C. albicans, S. sanguinis, and S. oralis. The antibacterial activity of the dentifrice was evaluated by the direct contact technique. Results. It was found that the highest antimicrobial activity was only present in pulp-based dentifrices against strains of S. mutans 21.0 ± 1.8, E. faecalis 16.3 ± 3.9, Actinomyces 22.1 ± 1.3, and Lactobacillus 21.0 ± 1.3. However, in comparison with other strains such as C. albicans, S. sanguinis, and S. oralis, the peel-based dendrifrice of Passiflora mollissima obtained the highest antimicrobial activity. Conclusion. The experimental dentifrice based on Passiflora mollissima had an antibacterial effect against the seven microbial strains during the first 24 and 48 hours.
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institution Kabale University
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publishDate 2019-01-01
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series International Journal of Dentistry
spelling doaj-art-6867b38702b5420594aaa4d5323b8e8e2025-02-03T01:22:26ZengWileyInternational Journal of Dentistry1687-87281687-87362019-01-01201910.1155/2019/90565909056590Development and Formulation of the Experimental Dentifrice Based on Passiflora mollissima (Tumbo) with and without Fluoride Anion: Antibacterial Activity on Seven Antimicrobial StrainsFrank Mayta-Tovalino0Eloy Gamboa1Richard Sánchez2Jorge Rios3Ramín Medina4Martín García5Jhonn Asencios6Professor of Stomatology School, Universidad Privada San Juan Bautista, Lima, PeruProfessor of Stomatology School, Universidad Privada San Juan Bautista, Lima, PeruProfessor of Stomatology School, Universidad Privada San Juan Bautista, Lima, PeruProfessor of Stomatology School, Universidad Privada San Juan Bautista, Lima, PeruStomatology School, Universidad Privada San Juan Bautista, Lima, PeruStomatology School, Universidad Privada San Juan Bautista, Lima, PeruStomatology School, Universidad Privada San Juan Bautista, Lima, PeruObjectives. To develop and formulate a new experimental dentifrice with and without fluoride based on the peel and the fruit of the Passiflora mollissima (tumbo) and also to evaluate its antimicrobial activity against seven bacterial strains. Methods. The sample was calculated using the mean comparison formula, obtaining wells (n = 12) for each of the strains evaluated: S. mutans, E. faecalis, Actinomyces, Lactobacillus, C. albicans, S. sanguinis, and S. oralis. The antibacterial activity of the dentifrice was evaluated by the direct contact technique. Results. It was found that the highest antimicrobial activity was only present in pulp-based dentifrices against strains of S. mutans 21.0 ± 1.8, E. faecalis 16.3 ± 3.9, Actinomyces 22.1 ± 1.3, and Lactobacillus 21.0 ± 1.3. However, in comparison with other strains such as C. albicans, S. sanguinis, and S. oralis, the peel-based dendrifrice of Passiflora mollissima obtained the highest antimicrobial activity. Conclusion. The experimental dentifrice based on Passiflora mollissima had an antibacterial effect against the seven microbial strains during the first 24 and 48 hours.http://dx.doi.org/10.1155/2019/9056590
spellingShingle Frank Mayta-Tovalino
Eloy Gamboa
Richard Sánchez
Jorge Rios
Ramín Medina
Martín García
Jhonn Asencios
Development and Formulation of the Experimental Dentifrice Based on Passiflora mollissima (Tumbo) with and without Fluoride Anion: Antibacterial Activity on Seven Antimicrobial Strains
International Journal of Dentistry
title Development and Formulation of the Experimental Dentifrice Based on Passiflora mollissima (Tumbo) with and without Fluoride Anion: Antibacterial Activity on Seven Antimicrobial Strains
title_full Development and Formulation of the Experimental Dentifrice Based on Passiflora mollissima (Tumbo) with and without Fluoride Anion: Antibacterial Activity on Seven Antimicrobial Strains
title_fullStr Development and Formulation of the Experimental Dentifrice Based on Passiflora mollissima (Tumbo) with and without Fluoride Anion: Antibacterial Activity on Seven Antimicrobial Strains
title_full_unstemmed Development and Formulation of the Experimental Dentifrice Based on Passiflora mollissima (Tumbo) with and without Fluoride Anion: Antibacterial Activity on Seven Antimicrobial Strains
title_short Development and Formulation of the Experimental Dentifrice Based on Passiflora mollissima (Tumbo) with and without Fluoride Anion: Antibacterial Activity on Seven Antimicrobial Strains
title_sort development and formulation of the experimental dentifrice based on passiflora mollissima tumbo with and without fluoride anion antibacterial activity on seven antimicrobial strains
url http://dx.doi.org/10.1155/2019/9056590
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