Cardioprotective effects of hUCMSCs-Exosi-EGR1 MN patch in MI/RI by modulating oxidative stress and mitophagy

Cardioprotective effects of hUCMSCs-Exosi-EGR1 MN patch in MI/RI by modulating oxidative stress and mitophagy

In an effort to address the detrimental effects of myocardial ischemia/reperfusion injury (MI/RI), this study introduces a novel therapeutic strategy that involves a microneedle (MN) patch loaded with exosomes derived from human umbilical cord mesenchymal stem cells (hUCMSCs) and carrying small inte...

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Bibliographic Details
Main Authors:	Chen Huang, Xun Zhang, Shi-Xiong Wu, Qing Chang, Zhi-Kun Zheng, Jing Xu
Format:	Article
Language:	English
Published:	Elsevier 2025-04-01
Series:	Materials Today Bio
Subjects:	Myocardial ischemia/reperfusion injury Exosomes EGR1 siRNA Microneedle patch Oxidative stress
Online Access:	http://www.sciencedirect.com/science/article/pii/S2590006425000584
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