Preparation and Characterization of Visible-Light-Activated Fe-N Co-Doped TiO2 and Its Photocatalytic Inactivation Effect on Leukemia Tumors
The Fe-N co-doped TiO2 nanocomposites were synthesized by a sol-gel method and characterized by scanning electron microscope (SEM), transmission electron microscope (TEM), X-ray diffraction (XRD), ultraviolet-visible absorption spectroscopy (UV-vis) and X-ray photoelectron spectroscopy (XPS). Then t...
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | International Journal of Photoenergy |
| Online Access: | http://dx.doi.org/10.1155/2012/631435 |
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| author | Kangqiang Huang Li Chen Jianwen Xiong Meixiang Liao |
| author_facet | Kangqiang Huang Li Chen Jianwen Xiong Meixiang Liao |
| author_sort | Kangqiang Huang |
| collection | DOAJ |
| description | The Fe-N co-doped TiO2 nanocomposites were synthesized by a sol-gel method and characterized by scanning electron microscope (SEM), transmission electron microscope (TEM), X-ray diffraction (XRD), ultraviolet-visible absorption spectroscopy (UV-vis) and X-ray photoelectron spectroscopy (XPS). Then the photocatalytic inactivation of Fe-N-doped TiO2 on leukemia tumors was investigated by using Cell Counting Kit-8 (CCK-8) assay. Additionally, the ultrastructural morphology and apoptotic percentage of treated cells were also studied. The experimental results showed that the growth of leukemic HL60 cells was significantly inhibited in groups treated with TiO2 nanoparticles and the photocatalytic activity of Fe-N-TiO2 was significantly higher than that of Fe-TiO2 and N-TiO2, indicating that the photocatalytic efficiency could be effectively enhanced by the modification of Fe-N. Furthermore, when 2 wt% Fe-N-TiO2 nanocomposites at a final concentration of 200 μg/mL were used, the inactivation efficiency of 78.5% was achieved after 30-minute light therapy. |
| format | Article |
| id | doaj-art-685a87737c6d44cb99984ee4a33b762d |
| institution | Kabale University |
| issn | 1110-662X 1687-529X |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Photoenergy |
| spelling | doaj-art-685a87737c6d44cb99984ee4a33b762d2025-02-03T06:10:54ZengWileyInternational Journal of Photoenergy1110-662X1687-529X2012-01-01201210.1155/2012/631435631435Preparation and Characterization of Visible-Light-Activated Fe-N Co-Doped TiO2 and Its Photocatalytic Inactivation Effect on Leukemia TumorsKangqiang Huang0Li Chen1Jianwen Xiong2Meixiang Liao3Laboratory of Quantum Information Technology, School of Physics and Telecommunication Engineering, South China Normal University, Guangzhou 510006, ChinaDepartment of Physics and Optoelectronic Engineering, Guangdong University of Technology, Guangzhou 510006, ChinaLaboratory of Quantum Information Technology, School of Physics and Telecommunication Engineering, South China Normal University, Guangzhou 510006, ChinaSchool of Physics and Engineering, Sun Yat-Sen University, Guangzhou 510275, ChinaThe Fe-N co-doped TiO2 nanocomposites were synthesized by a sol-gel method and characterized by scanning electron microscope (SEM), transmission electron microscope (TEM), X-ray diffraction (XRD), ultraviolet-visible absorption spectroscopy (UV-vis) and X-ray photoelectron spectroscopy (XPS). Then the photocatalytic inactivation of Fe-N-doped TiO2 on leukemia tumors was investigated by using Cell Counting Kit-8 (CCK-8) assay. Additionally, the ultrastructural morphology and apoptotic percentage of treated cells were also studied. The experimental results showed that the growth of leukemic HL60 cells was significantly inhibited in groups treated with TiO2 nanoparticles and the photocatalytic activity of Fe-N-TiO2 was significantly higher than that of Fe-TiO2 and N-TiO2, indicating that the photocatalytic efficiency could be effectively enhanced by the modification of Fe-N. Furthermore, when 2 wt% Fe-N-TiO2 nanocomposites at a final concentration of 200 μg/mL were used, the inactivation efficiency of 78.5% was achieved after 30-minute light therapy.http://dx.doi.org/10.1155/2012/631435 |
| spellingShingle | Kangqiang Huang Li Chen Jianwen Xiong Meixiang Liao Preparation and Characterization of Visible-Light-Activated Fe-N Co-Doped TiO2 and Its Photocatalytic Inactivation Effect on Leukemia Tumors International Journal of Photoenergy |
| title | Preparation and Characterization of Visible-Light-Activated Fe-N Co-Doped TiO2 and Its Photocatalytic Inactivation Effect on Leukemia Tumors |
| title_full | Preparation and Characterization of Visible-Light-Activated Fe-N Co-Doped TiO2 and Its Photocatalytic Inactivation Effect on Leukemia Tumors |
| title_fullStr | Preparation and Characterization of Visible-Light-Activated Fe-N Co-Doped TiO2 and Its Photocatalytic Inactivation Effect on Leukemia Tumors |
| title_full_unstemmed | Preparation and Characterization of Visible-Light-Activated Fe-N Co-Doped TiO2 and Its Photocatalytic Inactivation Effect on Leukemia Tumors |
| title_short | Preparation and Characterization of Visible-Light-Activated Fe-N Co-Doped TiO2 and Its Photocatalytic Inactivation Effect on Leukemia Tumors |
| title_sort | preparation and characterization of visible light activated fe n co doped tio2 and its photocatalytic inactivation effect on leukemia tumors |
| url | http://dx.doi.org/10.1155/2012/631435 |
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