Lipoprotein Signal Peptide as Adjuvants: Leveraging Lipobox-Driven TLR2 Activation in Modern Vaccine Design

Lipoprotein Signal Peptide as Adjuvants: Leveraging Lipobox-Driven TLR2 Activation in Modern Vaccine Design

Toll-like receptor 2 (TLR2) signaling is a pivotal component of immune system activation, and it is closely linked to the lipidation of bacterial proteins. This lipidation is guided by bacterial signal peptides (SPs), which ensure the precise targeting and membrane anchoring of these proteins. The l...

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Bibliographic Details
Main Authors: Muhammad Umar, Haroon Afzal, Asad Murtaza, Li-Ting Cheng
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Vaccines
Subjects:
lipobox
SP
TLR2
adjuvant
bacterial lipoprotein
Online Access:https://www.mdpi.com/2076-393X/13/1/36
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