The Genus Spilanthes Ethnopharmacology, Phytochemistry, and Pharmacological Properties: A Review

Spilanthes spp. are popular, over-the-counter remedies; they are sold over the internet under various names and are widely used in traditional medicine in various cultures. This review will summarize the important reports on the ethnopharmacology, botany, phytochemistry, and pharmacological proper...

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Main Authors: Jayaraj Paulraj, Raghavan Govindarajan, Pushpangadan Palpu
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:Advances in Pharmacological Sciences
Online Access:http://dx.doi.org/10.1155/2013/510298
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author Jayaraj Paulraj
Raghavan Govindarajan
Pushpangadan Palpu
author_facet Jayaraj Paulraj
Raghavan Govindarajan
Pushpangadan Palpu
author_sort Jayaraj Paulraj
collection DOAJ
description Spilanthes spp. are popular, over-the-counter remedies; they are sold over the internet under various names and are widely used in traditional medicine in various cultures. This review will summarize the important reports on the ethnopharmacology, botany, phytochemistry, and pharmacological properties as described in the literature from recent years (1920 to 2013). Spilanthes spp. are used for more than 60 types of disorders. They are reported to contain a number of biologically active phytochemicals, although a large number of ethnopharmacological uses have been documented; only a few of these species have been investigated for their chemical and biological activities. The studies are carried out mainly on Spilanthes extracts and a few metabolites substantiate the uses of these plants in traditional medicine. Well-conducted pharmacological studies are still needed for several traditional indications, and the mechanisms of action by which the plant extracts and the active compounds exert their pharmacological effects remain to be studied. They are predominantly used as extracts in personal care products, traditional medicines, and the pharmaceutical and culinary areas. Suggestions are made regarding some of the possible mechanisms of action as to how the known compounds may exert their biological activity.
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spelling doaj-art-6851fab7c1ff41d0959c7f1516ed6d2c2025-02-03T05:51:51ZengWileyAdvances in Pharmacological Sciences1687-63341687-63422013-01-01201310.1155/2013/510298510298The Genus Spilanthes Ethnopharmacology, Phytochemistry, and Pharmacological Properties: A ReviewJayaraj Paulraj0Raghavan Govindarajan1Pushpangadan Palpu2Department of Pharmacy, Periyar Maniammai University, Vallam, Thanjavur, TamilNadu 613403, IndiaPharmacognosy and Ethnopharmacology Division, National Botanical Research Institute, Lucknow 226001, IndiaAmity Institute of Herbal Product Research, Trivandrum, Kerala 695005, IndiaSpilanthes spp. are popular, over-the-counter remedies; they are sold over the internet under various names and are widely used in traditional medicine in various cultures. This review will summarize the important reports on the ethnopharmacology, botany, phytochemistry, and pharmacological properties as described in the literature from recent years (1920 to 2013). Spilanthes spp. are used for more than 60 types of disorders. They are reported to contain a number of biologically active phytochemicals, although a large number of ethnopharmacological uses have been documented; only a few of these species have been investigated for their chemical and biological activities. The studies are carried out mainly on Spilanthes extracts and a few metabolites substantiate the uses of these plants in traditional medicine. Well-conducted pharmacological studies are still needed for several traditional indications, and the mechanisms of action by which the plant extracts and the active compounds exert their pharmacological effects remain to be studied. They are predominantly used as extracts in personal care products, traditional medicines, and the pharmaceutical and culinary areas. Suggestions are made regarding some of the possible mechanisms of action as to how the known compounds may exert their biological activity.http://dx.doi.org/10.1155/2013/510298
spellingShingle Jayaraj Paulraj
Raghavan Govindarajan
Pushpangadan Palpu
The Genus Spilanthes Ethnopharmacology, Phytochemistry, and Pharmacological Properties: A Review
Advances in Pharmacological Sciences
title The Genus Spilanthes Ethnopharmacology, Phytochemistry, and Pharmacological Properties: A Review
title_full The Genus Spilanthes Ethnopharmacology, Phytochemistry, and Pharmacological Properties: A Review
title_fullStr The Genus Spilanthes Ethnopharmacology, Phytochemistry, and Pharmacological Properties: A Review
title_full_unstemmed The Genus Spilanthes Ethnopharmacology, Phytochemistry, and Pharmacological Properties: A Review
title_short The Genus Spilanthes Ethnopharmacology, Phytochemistry, and Pharmacological Properties: A Review
title_sort genus spilanthes ethnopharmacology phytochemistry and pharmacological properties a review
url http://dx.doi.org/10.1155/2013/510298
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