Estimation of the Corneal Young’s Modulus In Vivo Based on a Fluid-Filled Spherical-Shell Model with Scheimpflug Imaging
Current intraocular pressure (IOP) measurement using air puff could be erroneous without applying proper corrections. Although noncontact tonometry is not considered to be accurate, it is still popularly used by eye clinics. It is thus necessary to extract the correct information from their results....
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| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2017-01-01
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| Series: | Journal of Ophthalmology |
| Online Access: | http://dx.doi.org/10.1155/2017/5410143 |
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| author | Po-Jen Shih Chun-Ju Huang Tzu-Han Huang Hung-Chou Lin Jia-Yush Yen I-Jong Wang Hui-Jyun Cao Wen-Pin Shih Chi-An Dai |
| author_facet | Po-Jen Shih Chun-Ju Huang Tzu-Han Huang Hung-Chou Lin Jia-Yush Yen I-Jong Wang Hui-Jyun Cao Wen-Pin Shih Chi-An Dai |
| author_sort | Po-Jen Shih |
| collection | DOAJ |
| description | Current intraocular pressure (IOP) measurement using air puff could be erroneous without applying proper corrections. Although noncontact tonometry is not considered to be accurate, it is still popularly used by eye clinics. It is thus necessary to extract the correct information from their results. This study proposes a practical approach to correctly measure IOP in vivo. By embedding a new model-based correction to the Corvis® ST, we can extract the corneal Young’s modulus from the patient data. This Young’s modulus can be used to correct the IOP readings. The tests were applied to 536 right eyes of 536 healthy subjects (228 male and 308 female) between March of 2012 and April of 2016. The tests were applied to patients at the Department of Ophthalmology, National Taiwan University Hospital and the Hung-Chuo Eye Clinics. The statistical analysis showed that the value for the Young’s modulus was independent of all the other parameters collected from the Corvis ST, including the corneal thickness and the intraocular pressure. Therefore, it is important to independently measure the Young’s modulus instead of depending on the correlation with the other parameters. This study adds the methodology of measuring corneal stiffness in vivo for ophthalmologists’ reference in diagnosis. |
| format | Article |
| id | doaj-art-684af72c988e48e281aa8e38094fef6d |
| institution | Kabale University |
| issn | 2090-004X 2090-0058 |
| language | English |
| publishDate | 2017-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Ophthalmology |
| spelling | doaj-art-684af72c988e48e281aa8e38094fef6d2025-02-03T01:10:45ZengWileyJournal of Ophthalmology2090-004X2090-00582017-01-01201710.1155/2017/54101435410143Estimation of the Corneal Young’s Modulus In Vivo Based on a Fluid-Filled Spherical-Shell Model with Scheimpflug ImagingPo-Jen Shih0Chun-Ju Huang1Tzu-Han Huang2Hung-Chou Lin3Jia-Yush Yen4I-Jong Wang5Hui-Jyun Cao6Wen-Pin Shih7Chi-An Dai8Department of Civil and Environmental Engineering, National University of Kaohsiung, Kaohsiung, TaiwanDepartment of Mechanical Engineering, National Taiwan University, Taipei, TaiwanDepartment of Mechanical Engineering, National Taiwan University, Taipei, TaiwanDr. Lin’s Eye Clinic and Laser Vision Correction Center, Taoyuan City, TaiwanDepartment of Mechanical Engineering, National Taiwan University, Taipei, TaiwanDepartment of Ophthalmology, College of Medicine, National Taiwan University, Taipei, TaiwanDepartment of Mechanical Engineering, National Taiwan University, Taipei, TaiwanDepartment of Mechanical Engineering, National Taiwan University, Taipei, TaiwanDepartment of Chemical Engineering, National Taiwan University, Taipei, TaiwanCurrent intraocular pressure (IOP) measurement using air puff could be erroneous without applying proper corrections. Although noncontact tonometry is not considered to be accurate, it is still popularly used by eye clinics. It is thus necessary to extract the correct information from their results. This study proposes a practical approach to correctly measure IOP in vivo. By embedding a new model-based correction to the Corvis® ST, we can extract the corneal Young’s modulus from the patient data. This Young’s modulus can be used to correct the IOP readings. The tests were applied to 536 right eyes of 536 healthy subjects (228 male and 308 female) between March of 2012 and April of 2016. The tests were applied to patients at the Department of Ophthalmology, National Taiwan University Hospital and the Hung-Chuo Eye Clinics. The statistical analysis showed that the value for the Young’s modulus was independent of all the other parameters collected from the Corvis ST, including the corneal thickness and the intraocular pressure. Therefore, it is important to independently measure the Young’s modulus instead of depending on the correlation with the other parameters. This study adds the methodology of measuring corneal stiffness in vivo for ophthalmologists’ reference in diagnosis.http://dx.doi.org/10.1155/2017/5410143 |
| spellingShingle | Po-Jen Shih Chun-Ju Huang Tzu-Han Huang Hung-Chou Lin Jia-Yush Yen I-Jong Wang Hui-Jyun Cao Wen-Pin Shih Chi-An Dai Estimation of the Corneal Young’s Modulus In Vivo Based on a Fluid-Filled Spherical-Shell Model with Scheimpflug Imaging Journal of Ophthalmology |
| title | Estimation of the Corneal Young’s Modulus In Vivo Based on a Fluid-Filled Spherical-Shell Model with Scheimpflug Imaging |
| title_full | Estimation of the Corneal Young’s Modulus In Vivo Based on a Fluid-Filled Spherical-Shell Model with Scheimpflug Imaging |
| title_fullStr | Estimation of the Corneal Young’s Modulus In Vivo Based on a Fluid-Filled Spherical-Shell Model with Scheimpflug Imaging |
| title_full_unstemmed | Estimation of the Corneal Young’s Modulus In Vivo Based on a Fluid-Filled Spherical-Shell Model with Scheimpflug Imaging |
| title_short | Estimation of the Corneal Young’s Modulus In Vivo Based on a Fluid-Filled Spherical-Shell Model with Scheimpflug Imaging |
| title_sort | estimation of the corneal young s modulus in vivo based on a fluid filled spherical shell model with scheimpflug imaging |
| url | http://dx.doi.org/10.1155/2017/5410143 |
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