Detection of Phosphorylated Alpha-Synuclein in the Muscularis Propria of the Gastrointestinal Tract Is a Sensitive Predictor for Parkinson’s Disease
Background. Parkinson’s disease (PD) is a neurodegenerative disorder characterized by motor and nonmotor impairments, including constipation. Lewy bodies and neurites, the pathological hallmarks of PD, are found in the enteric nervous system (ENS) as well as the central nervous system. Constipation...
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Main Authors: | Goichi Beck, Yumiko Hori, Yoshito Hayashi, Eiichi Morii, Tetsuo Takehara, Hideki Mochizuki |
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Format: | Article |
Language: | English |
Published: |
Wiley
2020-01-01
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Series: | Parkinson's Disease |
Online Access: | http://dx.doi.org/10.1155/2020/4687530 |
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