Musculoskeletal Manifestations of Sickle Cell Anaemia: A Pictorial Review
Sickle cell anaemia is an autosomal recessive genetic condition producing abnormal haemoglobin HbS molecules that result in stiff and sticky red blood cells leading to unpredictable episodes of microvascular occlusions. The clinical and radiological manifestations of sickle cell anaemia result from...
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| Format: | Article |
| Language: | English |
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Wiley
2011-01-01
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| Series: | Anemia |
| Online Access: | http://dx.doi.org/10.1155/2011/794283 |
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| _version_ | 1832568293698830336 |
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| author | A. Ganguly W. Boswell H. Aniq |
| author_facet | A. Ganguly W. Boswell H. Aniq |
| author_sort | A. Ganguly |
| collection | DOAJ |
| description | Sickle cell anaemia is an autosomal recessive genetic condition producing abnormal haemoglobin HbS molecules that result in stiff and sticky red blood cells leading to unpredictable episodes of microvascular occlusions. The clinical and radiological manifestations of sickle cell anaemia result from small vessel occlusion, leading to tissue ischemia/infarction and progressive end-organ damage. In this paper we discuss and illustrate the various musculoskeletal manifestations of sickle cell disease focusing primarily on marrow hyperplasia, osteomyelitis and septic arthritis, medullary and epiphyseal bone infarcts, growth defects, and soft tissue changes. |
| format | Article |
| id | doaj-art-6814c1a410d145608376369425682ca4 |
| institution | Kabale University |
| issn | 2090-1267 2090-1275 |
| language | English |
| publishDate | 2011-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Anemia |
| spelling | doaj-art-6814c1a410d145608376369425682ca42025-02-03T00:59:22ZengWileyAnemia2090-12672090-12752011-01-01201110.1155/2011/794283794283Musculoskeletal Manifestations of Sickle Cell Anaemia: A Pictorial ReviewA. Ganguly0W. Boswell1H. Aniq2Department of Radiology, Royal Liverpool University Hospital, Prescot Street, Liverpool L7 8XP, UKDepartment of Radiology, Royal Liverpool University Hospital, Prescot Street, Liverpool L7 8XP, UKDepartment of Radiology, Royal Liverpool University Hospital, Prescot Street, Liverpool L7 8XP, UKSickle cell anaemia is an autosomal recessive genetic condition producing abnormal haemoglobin HbS molecules that result in stiff and sticky red blood cells leading to unpredictable episodes of microvascular occlusions. The clinical and radiological manifestations of sickle cell anaemia result from small vessel occlusion, leading to tissue ischemia/infarction and progressive end-organ damage. In this paper we discuss and illustrate the various musculoskeletal manifestations of sickle cell disease focusing primarily on marrow hyperplasia, osteomyelitis and septic arthritis, medullary and epiphyseal bone infarcts, growth defects, and soft tissue changes.http://dx.doi.org/10.1155/2011/794283 |
| spellingShingle | A. Ganguly W. Boswell H. Aniq Musculoskeletal Manifestations of Sickle Cell Anaemia: A Pictorial Review Anemia |
| title | Musculoskeletal Manifestations of Sickle Cell Anaemia: A Pictorial Review |
| title_full | Musculoskeletal Manifestations of Sickle Cell Anaemia: A Pictorial Review |
| title_fullStr | Musculoskeletal Manifestations of Sickle Cell Anaemia: A Pictorial Review |
| title_full_unstemmed | Musculoskeletal Manifestations of Sickle Cell Anaemia: A Pictorial Review |
| title_short | Musculoskeletal Manifestations of Sickle Cell Anaemia: A Pictorial Review |
| title_sort | musculoskeletal manifestations of sickle cell anaemia a pictorial review |
| url | http://dx.doi.org/10.1155/2011/794283 |
| work_keys_str_mv | AT aganguly musculoskeletalmanifestationsofsicklecellanaemiaapictorialreview AT wboswell musculoskeletalmanifestationsofsicklecellanaemiaapictorialreview AT haniq musculoskeletalmanifestationsofsicklecellanaemiaapictorialreview |