TEMPTED: time-informed dimensionality reduction for longitudinal microbiome studies

TEMPTED: time-informed dimensionality reduction for longitudinal microbiome studies

Abstract Longitudinal studies are crucial for understanding complex microbiome dynamics and their link to health. We introduce TEMPoral TEnsor Decomposition (TEMPTED), a time-informed dimensionality reduction method for high-dimensional longitudinal data that treats time as a continuous variable, ef...

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Main Authors: Pixu Shi, Cameron Martino, Rungang Han, Stefan Janssen, Gregory Buck, Myrna Serrano, Kouros Owzar, Rob Knight, Liat Shenhav, Anru R. Zhang
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Genome Biology
Online Access:https://doi.org/10.1186/s13059-024-03453-x
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