Design and Implementation Guidelines for a Modular Spectral-Domain Optical Coherence Tomography Scanner

In the past decades, spectral-domain optical coherence tomography (SD-OCT) has transformed into a widely popular imaging technology which is used in many research and clinical applications. Despite such fast growth in the field, the technology has not been readily accessible to many research laborat...

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Main Authors: Farid Atry, Israel Jacob De La Rosa, Kevin R. Rarick, Ramin Pashaie
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:International Journal of Optics
Online Access:http://dx.doi.org/10.1155/2018/3726207
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author Farid Atry
Israel Jacob De La Rosa
Kevin R. Rarick
Ramin Pashaie
author_facet Farid Atry
Israel Jacob De La Rosa
Kevin R. Rarick
Ramin Pashaie
author_sort Farid Atry
collection DOAJ
description In the past decades, spectral-domain optical coherence tomography (SD-OCT) has transformed into a widely popular imaging technology which is used in many research and clinical applications. Despite such fast growth in the field, the technology has not been readily accessible to many research laboratories either due to the cost or inflexibility of the commercially available systems or due to the lack of essential knowledge in the field of optics to develop custom-made scanners that suit specific applications. This paper aims to provide a detailed discussion on the design and development process of a typical SD-OCT scanner. The effects of multiple design parameters, for the main optical and optomechanical components, on the overall performance of the imaging system are analyzed and discussions are provided to serve as a guideline for the development of a custom SD-OCT system. While this article can be generalized for different applications, we will demonstrate the design of a SD-OCT system and representative results for in vivo brain imaging. We explain procedures to measure the axial and transversal resolutions and field of view of the system and to understand the discrepancies between the experimental and theoretical values. The specific aim of this piece is to facilitate the process of constructing custom-made SD-OCT scanners for research groups with minimum understanding of concepts in optical design and medical imaging.
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institution Kabale University
issn 1687-9384
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spelling doaj-art-67fafc57ec004e07b8630c40afcfcf782025-02-03T01:21:00ZengWileyInternational Journal of Optics1687-93841687-93922018-01-01201810.1155/2018/37262073726207Design and Implementation Guidelines for a Modular Spectral-Domain Optical Coherence Tomography ScannerFarid Atry0Israel Jacob De La Rosa1Kevin R. Rarick2Ramin Pashaie3Department of Biomedical Engineering, University of Wisconsin–Madison, Madison, WI, USAElectrical Engineering Department, University of Wisconsin–Milwaukee, Milwaukee, WI, USADepartment of Pediatrics, Medical College of Wisconsin, Milwaukee, WI, USAElectrical Engineering Department, University of Wisconsin–Milwaukee, Milwaukee, WI, USAIn the past decades, spectral-domain optical coherence tomography (SD-OCT) has transformed into a widely popular imaging technology which is used in many research and clinical applications. Despite such fast growth in the field, the technology has not been readily accessible to many research laboratories either due to the cost or inflexibility of the commercially available systems or due to the lack of essential knowledge in the field of optics to develop custom-made scanners that suit specific applications. This paper aims to provide a detailed discussion on the design and development process of a typical SD-OCT scanner. The effects of multiple design parameters, for the main optical and optomechanical components, on the overall performance of the imaging system are analyzed and discussions are provided to serve as a guideline for the development of a custom SD-OCT system. While this article can be generalized for different applications, we will demonstrate the design of a SD-OCT system and representative results for in vivo brain imaging. We explain procedures to measure the axial and transversal resolutions and field of view of the system and to understand the discrepancies between the experimental and theoretical values. The specific aim of this piece is to facilitate the process of constructing custom-made SD-OCT scanners for research groups with minimum understanding of concepts in optical design and medical imaging.http://dx.doi.org/10.1155/2018/3726207
spellingShingle Farid Atry
Israel Jacob De La Rosa
Kevin R. Rarick
Ramin Pashaie
Design and Implementation Guidelines for a Modular Spectral-Domain Optical Coherence Tomography Scanner
International Journal of Optics
title Design and Implementation Guidelines for a Modular Spectral-Domain Optical Coherence Tomography Scanner
title_full Design and Implementation Guidelines for a Modular Spectral-Domain Optical Coherence Tomography Scanner
title_fullStr Design and Implementation Guidelines for a Modular Spectral-Domain Optical Coherence Tomography Scanner
title_full_unstemmed Design and Implementation Guidelines for a Modular Spectral-Domain Optical Coherence Tomography Scanner
title_short Design and Implementation Guidelines for a Modular Spectral-Domain Optical Coherence Tomography Scanner
title_sort design and implementation guidelines for a modular spectral domain optical coherence tomography scanner
url http://dx.doi.org/10.1155/2018/3726207
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AT kevinrrarick designandimplementationguidelinesforamodularspectraldomainopticalcoherencetomographyscanner
AT raminpashaie designandimplementationguidelinesforamodularspectraldomainopticalcoherencetomographyscanner