A Facile Synthesis of Highly Nitrogen-Doped Carbon Dots for Imaging and Detection in Biological Samples

A facile, green, and high-output hydrothermal synthesis was proposed for the fabrication of highly fluorescent nitrogen-doped carbon quantum dots (N-doped CDs). The nitrogen content in N-doped CDs reached 19.2% and demonstrated strong blue fluorescence emission was obtained with fluorescence quantum...

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Main Authors: Qianchun Zhang, Siqi Xie, Yanqun Yang, Yun Wu, Xingyi Wang, Jincheng Wu, Li Zhang, Junyu Chen, Yuan Wang
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:Journal of Analytical Methods in Chemistry
Online Access:http://dx.doi.org/10.1155/2018/7890937
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author Qianchun Zhang
Siqi Xie
Yanqun Yang
Yun Wu
Xingyi Wang
Jincheng Wu
Li Zhang
Junyu Chen
Yuan Wang
author_facet Qianchun Zhang
Siqi Xie
Yanqun Yang
Yun Wu
Xingyi Wang
Jincheng Wu
Li Zhang
Junyu Chen
Yuan Wang
author_sort Qianchun Zhang
collection DOAJ
description A facile, green, and high-output hydrothermal synthesis was proposed for the fabrication of highly fluorescent nitrogen-doped carbon quantum dots (N-doped CDs). The nitrogen content in N-doped CDs reached 19.2% and demonstrated strong blue fluorescence emission was obtained with fluorescence quantum yield (QY) of up to 32.9%, which exhibit high fluorescence quantum yield, high photostability, and excellent biocompatibility. The N-doped CDs possess high photostability, low toxicity, and excellent biocompatibility, based on which the N-doped CDs were successfully applied as a fluorescence probe for cell imaging. Moreover, it was then successfully demonstrated for sensitive and selective detection of Fe3+ in serum.
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id doaj-art-67f263e7902c4b22ab2195b823eb0da1
institution Kabale University
issn 2090-8865
2090-8873
language English
publishDate 2018-01-01
publisher Wiley
record_format Article
series Journal of Analytical Methods in Chemistry
spelling doaj-art-67f263e7902c4b22ab2195b823eb0da12025-02-03T07:24:33ZengWileyJournal of Analytical Methods in Chemistry2090-88652090-88732018-01-01201810.1155/2018/78909377890937A Facile Synthesis of Highly Nitrogen-Doped Carbon Dots for Imaging and Detection in Biological SamplesQianchun Zhang0Siqi Xie1Yanqun Yang2Yun Wu3Xingyi Wang4Jincheng Wu5Li Zhang6Junyu Chen7Yuan Wang8School of Biology and Chemistry, Xingyi Normal University for Nationalities, Xingyi 562400, ChinaSchool of Biology and Chemistry, Xingyi Normal University for Nationalities, Xingyi 562400, ChinaSchool of Biology and Chemistry, Xingyi Normal University for Nationalities, Xingyi 562400, ChinaSchool of Biology and Chemistry, Xingyi Normal University for Nationalities, Xingyi 562400, ChinaSchool of Biology and Chemistry, Xingyi Normal University for Nationalities, Xingyi 562400, ChinaSchool of Biology and Chemistry, Xingyi Normal University for Nationalities, Xingyi 562400, ChinaSchool of Biology and Chemistry, Xingyi Normal University for Nationalities, Xingyi 562400, ChinaSchool of Biology and Chemistry, Xingyi Normal University for Nationalities, Xingyi 562400, ChinaSchool of Biology and Chemistry, Xingyi Normal University for Nationalities, Xingyi 562400, ChinaA facile, green, and high-output hydrothermal synthesis was proposed for the fabrication of highly fluorescent nitrogen-doped carbon quantum dots (N-doped CDs). The nitrogen content in N-doped CDs reached 19.2% and demonstrated strong blue fluorescence emission was obtained with fluorescence quantum yield (QY) of up to 32.9%, which exhibit high fluorescence quantum yield, high photostability, and excellent biocompatibility. The N-doped CDs possess high photostability, low toxicity, and excellent biocompatibility, based on which the N-doped CDs were successfully applied as a fluorescence probe for cell imaging. Moreover, it was then successfully demonstrated for sensitive and selective detection of Fe3+ in serum.http://dx.doi.org/10.1155/2018/7890937
spellingShingle Qianchun Zhang
Siqi Xie
Yanqun Yang
Yun Wu
Xingyi Wang
Jincheng Wu
Li Zhang
Junyu Chen
Yuan Wang
A Facile Synthesis of Highly Nitrogen-Doped Carbon Dots for Imaging and Detection in Biological Samples
Journal of Analytical Methods in Chemistry
title A Facile Synthesis of Highly Nitrogen-Doped Carbon Dots for Imaging and Detection in Biological Samples
title_full A Facile Synthesis of Highly Nitrogen-Doped Carbon Dots for Imaging and Detection in Biological Samples
title_fullStr A Facile Synthesis of Highly Nitrogen-Doped Carbon Dots for Imaging and Detection in Biological Samples
title_full_unstemmed A Facile Synthesis of Highly Nitrogen-Doped Carbon Dots for Imaging and Detection in Biological Samples
title_short A Facile Synthesis of Highly Nitrogen-Doped Carbon Dots for Imaging and Detection in Biological Samples
title_sort facile synthesis of highly nitrogen doped carbon dots for imaging and detection in biological samples
url http://dx.doi.org/10.1155/2018/7890937
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