Chitin, Chitosan, and Glycated Chitosan Regulate Immune Responses: The Novel Adjuvants for Cancer Vaccine

With the development of cancer immunotherapy, cancer vaccine has become a novel modality for cancer treatment, and the important role of adjuvant has been realized recently. Chitin, chitosan, and their derivatives have shown their advantages as adjuvants for cancer vaccine. In this paper, the adjuva...

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Main Authors: Xiaosong Li, Min Min, Nan Du, Ying Gu, Tomas Hode, Mark Naylor, Dianjun Chen, Robert E. Nordquist, Wei R. Chen
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:Clinical and Developmental Immunology
Online Access:http://dx.doi.org/10.1155/2013/387023
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author Xiaosong Li
Min Min
Nan Du
Ying Gu
Tomas Hode
Mark Naylor
Dianjun Chen
Robert E. Nordquist
Wei R. Chen
author_facet Xiaosong Li
Min Min
Nan Du
Ying Gu
Tomas Hode
Mark Naylor
Dianjun Chen
Robert E. Nordquist
Wei R. Chen
author_sort Xiaosong Li
collection DOAJ
description With the development of cancer immunotherapy, cancer vaccine has become a novel modality for cancer treatment, and the important role of adjuvant has been realized recently. Chitin, chitosan, and their derivatives have shown their advantages as adjuvants for cancer vaccine. In this paper, the adjuvant properties of chitin and chitosan were discussed, and some detailed information about glycated chitosan and chitosan nanoparticles was also presented to illustrate the trend for future development.
format Article
id doaj-art-67eecdea340144d4b8fc1c17c139ab8b
institution OA Journals
issn 1740-2522
1740-2530
language English
publishDate 2013-01-01
publisher Wiley
record_format Article
series Clinical and Developmental Immunology
spelling doaj-art-67eecdea340144d4b8fc1c17c139ab8b2025-08-20T02:24:03ZengWileyClinical and Developmental Immunology1740-25221740-25302013-01-01201310.1155/2013/387023387023Chitin, Chitosan, and Glycated Chitosan Regulate Immune Responses: The Novel Adjuvants for Cancer VaccineXiaosong Li0Min Min1Nan Du2Ying Gu3Tomas Hode4Mark Naylor5Dianjun Chen6Robert E. Nordquist7Wei R. Chen8Department of Oncology, The First Affiliated Hospital of Chinese PLA General Hospital, Beijing 100048, ChinaDepartment of Gastroenterology, Affiliated Hospital of Academy of Military Medical Sciences, Beijing 100071, ChinaDepartment of Oncology, The First Affiliated Hospital of Chinese PLA General Hospital, Beijing 100048, ChinaDepartment of Laser Medicine, Chinese PLA General Hospital, Beijing 100853, ChinaImmunoPhotonics Inc., Columbia, MO 65211, USADermatology Associates of San Antonio, San Antonio, TX 78233, USADepartment of Oncology, The First Affiliated Hospital of Chinese PLA General Hospital, Beijing 100048, ChinaImmunoPhotonics Inc., Columbia, MO 65211, USADepartment of Engineering and Physics, University of Central Oklahoma, Edmond, OK 73034, USAWith the development of cancer immunotherapy, cancer vaccine has become a novel modality for cancer treatment, and the important role of adjuvant has been realized recently. Chitin, chitosan, and their derivatives have shown their advantages as adjuvants for cancer vaccine. In this paper, the adjuvant properties of chitin and chitosan were discussed, and some detailed information about glycated chitosan and chitosan nanoparticles was also presented to illustrate the trend for future development.http://dx.doi.org/10.1155/2013/387023
spellingShingle Xiaosong Li
Min Min
Nan Du
Ying Gu
Tomas Hode
Mark Naylor
Dianjun Chen
Robert E. Nordquist
Wei R. Chen
Chitin, Chitosan, and Glycated Chitosan Regulate Immune Responses: The Novel Adjuvants for Cancer Vaccine
Clinical and Developmental Immunology
title Chitin, Chitosan, and Glycated Chitosan Regulate Immune Responses: The Novel Adjuvants for Cancer Vaccine
title_full Chitin, Chitosan, and Glycated Chitosan Regulate Immune Responses: The Novel Adjuvants for Cancer Vaccine
title_fullStr Chitin, Chitosan, and Glycated Chitosan Regulate Immune Responses: The Novel Adjuvants for Cancer Vaccine
title_full_unstemmed Chitin, Chitosan, and Glycated Chitosan Regulate Immune Responses: The Novel Adjuvants for Cancer Vaccine
title_short Chitin, Chitosan, and Glycated Chitosan Regulate Immune Responses: The Novel Adjuvants for Cancer Vaccine
title_sort chitin chitosan and glycated chitosan regulate immune responses the novel adjuvants for cancer vaccine
url http://dx.doi.org/10.1155/2013/387023
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