Voltage-dependent anion channel 1 oligomerization regulates PANoptosis in retinal ischemia–reperfusion injury

Voltage-dependent anion channel 1 oligomerization regulates PANoptosis in retinal ischemia–reperfusion injury

Ischemia–reperfusion injury is a common pathophysiological mechanism in retinal degeneration. PANoptosis is a newly defined integral form of regulated cell death that combines the key features of pyroptosis, apoptosis, and necroptosis. Oligomerization of mitochondrial voltage-dependent anion channel...

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Bibliographic Details
Main Authors: Hao Wan, Xiaoxia Ban, Ye He, Yandi Yang, Ximin Hu, Lei Shang, Xinxing Wan, Qi Zhang, Kun Xiong
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2026-04-01
Series:Neural Regeneration Research
Subjects:
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
apoptosis
ischemia–reperfusion injury
mitochondrial dysfunction
necroptosis
oxidative stress
panoptosis
pyroptosis
reactive oxygen species
voltage-dependent anion channel 1
Online Access:https://journals.lww.com/10.4103/NRR.NRR-D-24-00674
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