Multi-assay assessment of cytotoxicity reveals multiple mechanisms of action in 3D microtissues
Abstract Cell viability assays are an integral component of toxicology and high-throughput drug screening studies; however, many assays rely on a single biomarker of cell death which provides an incomplete assessment of cell viability. Here, we introduce an innovative approach that combines data fro...
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Main Authors: | Ahbid Zein-Sabatto, Katerina St. Angelo, Samantha J. Madnick, Diane Hoffman-Kim, Jeffrey R. Morgan, Jonghwan Lee |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2025-01-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-025-86792-4 |
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