COVID-19: An Update on the Latest Therapeutic Agents
The COVID-19 pandemic has plagued the world for over three years since discovering the causative virus, SARS-CoV-2, in China. The rampant spread of the virus led to the loss of livelihoods of millions across the globe. This public health emergency prompted the rapid development of vaccines and trea...
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| Format: | Article |
| Language: | English |
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HH Publisher
2023-04-01
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| Series: | Progress in Microbes and Molecular Biology |
| Online Access: | https://journals.hh-publisher.com/index.php/pmmb/article/view/796 |
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| author | Ke-Yan Loo Loh Teng-Hern Tan Jodi Woan-Fei Law Kar-Wai Hong Kok-Gan Chan Vengadesh Letchumanan |
| author_facet | Ke-Yan Loo Loh Teng-Hern Tan Jodi Woan-Fei Law Kar-Wai Hong Kok-Gan Chan Vengadesh Letchumanan |
| author_sort | Ke-Yan Loo |
| collection | DOAJ |
| description |
The COVID-19 pandemic has plagued the world for over three years since discovering the causative virus, SARS-CoV-2, in China. The rampant spread of the virus led to the loss of livelihoods of millions across the globe. This public health emergency prompted the rapid development of vaccines and treatments to fight against viral infection. Vaccines against the viral infection started rolling out in late 2020, and the distribution of the vaccines worldwide managed to reduce the symptoms of COVID-19 and prevent outbreaks in local communities. However, COVID-19 infections are still prevalent, with patients suffering from severe symptoms which require oxygen support or mechanical ventilation. Thus, therapeutic agents for COVID-19 play a significant role in reducing the risk of disease progression into severe disease and improving hospitalized patients' clinical outcomes. Existing drugs such as remdesivir, molnupiravir, baricitinib, anakinra, and tocilizumab have been repurposed to treat COVID-19 earlier during the pandemic to meet the urgent demand for treatment. There are also novel antiviral and immunomodulating treatments (nirmatrelvir plus ritonavir, ensitrelvir, regdanvimab, sotrovimab, and vilobelimab) that were developed during the pandemic to fight against COVID-19 infections. These therapeutic agents have been reported to be effective and safe for use to treat COVID-19 infections of different severity. Nevertheless, continuous surveillance is imperative in ensuring that these treatment methods maintain efficacy and safety profiles in treating COVID-19 caused by different variants of the virus.
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| format | Article |
| id | doaj-art-67c8ef6419ab4ac6a85c920f38e8a356 |
| institution | Kabale University |
| issn | 2637-1049 |
| language | English |
| publishDate | 2023-04-01 |
| publisher | HH Publisher |
| record_format | Article |
| series | Progress in Microbes and Molecular Biology |
| spelling | doaj-art-67c8ef6419ab4ac6a85c920f38e8a3562025-02-04T08:39:57ZengHH PublisherProgress in Microbes and Molecular Biology2637-10492023-04-016110.36877/pmmb.0000329COVID-19: An Update on the Latest Therapeutic Agents Ke-Yan LooLoh Teng-Hern TanJodi Woan-Fei LawKar-Wai HongKok-Gan ChanVengadesh Letchumanan The COVID-19 pandemic has plagued the world for over three years since discovering the causative virus, SARS-CoV-2, in China. The rampant spread of the virus led to the loss of livelihoods of millions across the globe. This public health emergency prompted the rapid development of vaccines and treatments to fight against viral infection. Vaccines against the viral infection started rolling out in late 2020, and the distribution of the vaccines worldwide managed to reduce the symptoms of COVID-19 and prevent outbreaks in local communities. However, COVID-19 infections are still prevalent, with patients suffering from severe symptoms which require oxygen support or mechanical ventilation. Thus, therapeutic agents for COVID-19 play a significant role in reducing the risk of disease progression into severe disease and improving hospitalized patients' clinical outcomes. Existing drugs such as remdesivir, molnupiravir, baricitinib, anakinra, and tocilizumab have been repurposed to treat COVID-19 earlier during the pandemic to meet the urgent demand for treatment. There are also novel antiviral and immunomodulating treatments (nirmatrelvir plus ritonavir, ensitrelvir, regdanvimab, sotrovimab, and vilobelimab) that were developed during the pandemic to fight against COVID-19 infections. These therapeutic agents have been reported to be effective and safe for use to treat COVID-19 infections of different severity. Nevertheless, continuous surveillance is imperative in ensuring that these treatment methods maintain efficacy and safety profiles in treating COVID-19 caused by different variants of the virus. https://journals.hh-publisher.com/index.php/pmmb/article/view/796 |
| spellingShingle | Ke-Yan Loo Loh Teng-Hern Tan Jodi Woan-Fei Law Kar-Wai Hong Kok-Gan Chan Vengadesh Letchumanan COVID-19: An Update on the Latest Therapeutic Agents Progress in Microbes and Molecular Biology |
| title | COVID-19: An Update on the Latest Therapeutic Agents |
| title_full | COVID-19: An Update on the Latest Therapeutic Agents |
| title_fullStr | COVID-19: An Update on the Latest Therapeutic Agents |
| title_full_unstemmed | COVID-19: An Update on the Latest Therapeutic Agents |
| title_short | COVID-19: An Update on the Latest Therapeutic Agents |
| title_sort | covid 19 an update on the latest therapeutic agents |
| url | https://journals.hh-publisher.com/index.php/pmmb/article/view/796 |
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