Pituitary Adenoma and Hyperprolactinemia Accompanied by Idiopathic Granulomatous Mastitis

Idiopathic granulomatous mastitis (IGM) is a rare chronic inflammatory disease of the breast, and its etiology remains not fully elucidated. IGM is observed more often in patients with autoimmune disease. Hyperprolactinemia is observed during pregnancy, lactation, and a history of oral contraceptive...

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Main Authors: Sebahattin Destek, Vahit Onur Gul, Serkan Ahioglu, Kursat Rahmi Serin
Format: Article
Language:English
Published: Wiley 2017-01-01
Series:Case Reports in Endocrinology
Online Access:http://dx.doi.org/10.1155/2017/3974291
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author Sebahattin Destek
Vahit Onur Gul
Serkan Ahioglu
Kursat Rahmi Serin
author_facet Sebahattin Destek
Vahit Onur Gul
Serkan Ahioglu
Kursat Rahmi Serin
author_sort Sebahattin Destek
collection DOAJ
description Idiopathic granulomatous mastitis (IGM) is a rare chronic inflammatory disease of the breast, and its etiology remains not fully elucidated. IGM is observed more often in patients with autoimmune disease. Hyperprolactinemia is observed during pregnancy, lactation, and a history of oral contraceptive use. A 39-year-old patient with no history of oral contraceptive use presented with complaints such as redness, pain, and swelling in her left breast. Ultrasound and magnetic resonance imaging (MRI) revealed a suspicious inflamed mass lesion. Core biopsy was performed to exclude breast cancer and to further diagnose. The breast abscess was drained and steroids were given for treatment. In order to monitor any progression during the three months of treatment, hormone levels were routinely examined. Prolactin level was above the reference range, and pituitary MRI revealed a pituitary prolactinoma. After treatment with prolactin inhibitors, IGM also improved with hyperprolactinemia. This report emphasizes attention to hyperprolactinemia in cases of IGM diagnosis and treatment.
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series Case Reports in Endocrinology
spelling doaj-art-67552d41ac5b41d5be83db3627d564b12025-02-03T05:50:28ZengWileyCase Reports in Endocrinology2090-65012090-651X2017-01-01201710.1155/2017/39742913974291Pituitary Adenoma and Hyperprolactinemia Accompanied by Idiopathic Granulomatous MastitisSebahattin Destek0Vahit Onur Gul1Serkan Ahioglu2Kursat Rahmi Serin3Department of General Surgery, Bezmialem Vakıf University School of Medicine, Istanbul, TurkeyGeneral Surgery Department, Edremit Government Hospital, Edremit, 10300 Balikesir, TurkeyBiochemistry Department, Edremit State Hospital, Edremit, 10300 Balikesir, TurkeyGeneral Surgery Department, Liv Hospital, Ulus, Istanbul, TurkeyIdiopathic granulomatous mastitis (IGM) is a rare chronic inflammatory disease of the breast, and its etiology remains not fully elucidated. IGM is observed more often in patients with autoimmune disease. Hyperprolactinemia is observed during pregnancy, lactation, and a history of oral contraceptive use. A 39-year-old patient with no history of oral contraceptive use presented with complaints such as redness, pain, and swelling in her left breast. Ultrasound and magnetic resonance imaging (MRI) revealed a suspicious inflamed mass lesion. Core biopsy was performed to exclude breast cancer and to further diagnose. The breast abscess was drained and steroids were given for treatment. In order to monitor any progression during the three months of treatment, hormone levels were routinely examined. Prolactin level was above the reference range, and pituitary MRI revealed a pituitary prolactinoma. After treatment with prolactin inhibitors, IGM also improved with hyperprolactinemia. This report emphasizes attention to hyperprolactinemia in cases of IGM diagnosis and treatment.http://dx.doi.org/10.1155/2017/3974291
spellingShingle Sebahattin Destek
Vahit Onur Gul
Serkan Ahioglu
Kursat Rahmi Serin
Pituitary Adenoma and Hyperprolactinemia Accompanied by Idiopathic Granulomatous Mastitis
Case Reports in Endocrinology
title Pituitary Adenoma and Hyperprolactinemia Accompanied by Idiopathic Granulomatous Mastitis
title_full Pituitary Adenoma and Hyperprolactinemia Accompanied by Idiopathic Granulomatous Mastitis
title_fullStr Pituitary Adenoma and Hyperprolactinemia Accompanied by Idiopathic Granulomatous Mastitis
title_full_unstemmed Pituitary Adenoma and Hyperprolactinemia Accompanied by Idiopathic Granulomatous Mastitis
title_short Pituitary Adenoma and Hyperprolactinemia Accompanied by Idiopathic Granulomatous Mastitis
title_sort pituitary adenoma and hyperprolactinemia accompanied by idiopathic granulomatous mastitis
url http://dx.doi.org/10.1155/2017/3974291
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AT serkanahioglu pituitaryadenomaandhyperprolactinemiaaccompaniedbyidiopathicgranulomatousmastitis
AT kursatrahmiserin pituitaryadenomaandhyperprolactinemiaaccompaniedbyidiopathicgranulomatousmastitis