Rapid Determination of Pemetrexed Concentration and Distribution in Human Breast Cancer Cells (McF-7) Based on UHPLC-MS/MS

Rapid Determination of Pemetrexed Concentration and Distribution in Human Breast Cancer Cells (McF-7) Based on UHPLC-MS/MS

Cell is the basic unit of structure and function of all living bodies. The study of intracellular drug concentration distribution is helpful to understand the drug efficacy of target site. Pemetrexed is a new multitarget folate antagonist with pyrrolidine group as its core structure. An ultra high-p...

Full description

Saved in:
Bibliographic Details
Main Authors: Mengwei Zhang, Zhipeng Wang, Qiqiang Zhang, Qing Ye, Fengjing Xu, Lili Cui, Yanping Liu, Shouhong Gao, Wansheng Chen, Yan Liu
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:International Journal of Analytical Chemistry
Online Access:http://dx.doi.org/10.1155/2021/6614332
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items