Adult ADHD Medications and Their Cardiovascular Implications

Attention-deficit/hyperactivity disorder (ADHD) is a chronic neurobiological disorder exhibited by difficulty maintaining attention, as well as hyperactivity and impulsive behavior. Central nervous system (CNS) stimulants are the first line of treatment for ADHD. With the increase in number of adult...

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Main Authors: A. Sinha, O. Lewis, R. Kumar, S. L. H. Yeruva, B. H. Curry
Format: Article
Language:English
Published: Wiley 2016-01-01
Series:Case Reports in Cardiology
Online Access:http://dx.doi.org/10.1155/2016/2343691
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author A. Sinha
O. Lewis
R. Kumar
S. L. H. Yeruva
B. H. Curry
author_facet A. Sinha
O. Lewis
R. Kumar
S. L. H. Yeruva
B. H. Curry
author_sort A. Sinha
collection DOAJ
description Attention-deficit/hyperactivity disorder (ADHD) is a chronic neurobiological disorder exhibited by difficulty maintaining attention, as well as hyperactivity and impulsive behavior. Central nervous system (CNS) stimulants are the first line of treatment for ADHD. With the increase in number of adults on CNS stimulants, the question that arises is how well do we understand the long-term cardiovascular effects of these drugs. There has been increasing concern that adults with ADHD are at greater risk for developing adverse cardiovascular events such as sudden death, myocardial infarction, and stroke as compared to pediatric population. Cardiovascular response attributed to ADHD medication has mainly been observed in heart rate and blood pressure elevations, while less is known about the etiology of rare cardiovascular events like acute myocardial infarction (AMI), arrhythmia, and cardiomyopathy and its long-term sequelae. We present a unique case of AMI in an adult taking Adderall (mixed amphetamine salts) and briefly discuss the literature relevant to the cardiovascular safety of CNS stimulants for adult ADHD.
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spelling doaj-art-671941c1a7114de7a35144e96b2c81f92025-02-03T01:02:59ZengWileyCase Reports in Cardiology2090-64042090-64122016-01-01201610.1155/2016/23436912343691Adult ADHD Medications and Their Cardiovascular ImplicationsA. Sinha0O. Lewis1R. Kumar2S. L. H. Yeruva3B. H. Curry4Division of Cardiology, Saint Luke’s University Health Network, 801 Ostrum Street, Bethlehem, PA 18015, USADivision of Pulmonary Medicine, Department of Internal Medicine, Howard University Hospital, 2041 Georgia Avenue, Washington, DC 20060, USADepartment of Internal Medicine, Howard University Hospital, 2041 Georgia Avenue, Washington, DC 20060, USADivision of Hematology & Oncology, Department of Internal Medicine, Howard University Hospital, 2041 Georgia Avenue, Washington, DC 20060, USADivision of Cardiology, Howard University Hospital, 2041 Georgia Avenue, Washington, DC 20060, USAAttention-deficit/hyperactivity disorder (ADHD) is a chronic neurobiological disorder exhibited by difficulty maintaining attention, as well as hyperactivity and impulsive behavior. Central nervous system (CNS) stimulants are the first line of treatment for ADHD. With the increase in number of adults on CNS stimulants, the question that arises is how well do we understand the long-term cardiovascular effects of these drugs. There has been increasing concern that adults with ADHD are at greater risk for developing adverse cardiovascular events such as sudden death, myocardial infarction, and stroke as compared to pediatric population. Cardiovascular response attributed to ADHD medication has mainly been observed in heart rate and blood pressure elevations, while less is known about the etiology of rare cardiovascular events like acute myocardial infarction (AMI), arrhythmia, and cardiomyopathy and its long-term sequelae. We present a unique case of AMI in an adult taking Adderall (mixed amphetamine salts) and briefly discuss the literature relevant to the cardiovascular safety of CNS stimulants for adult ADHD.http://dx.doi.org/10.1155/2016/2343691
spellingShingle A. Sinha
O. Lewis
R. Kumar
S. L. H. Yeruva
B. H. Curry
Adult ADHD Medications and Their Cardiovascular Implications
Case Reports in Cardiology
title Adult ADHD Medications and Their Cardiovascular Implications
title_full Adult ADHD Medications and Their Cardiovascular Implications
title_fullStr Adult ADHD Medications and Their Cardiovascular Implications
title_full_unstemmed Adult ADHD Medications and Their Cardiovascular Implications
title_short Adult ADHD Medications and Their Cardiovascular Implications
title_sort adult adhd medications and their cardiovascular implications
url http://dx.doi.org/10.1155/2016/2343691
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