Association between dietary carotenoid intakes and the risk of asthma in adults: a cross-sectional study of NHANES, 2007–2012
Objective To investigate the association between dietary carotenoid intake and asthma using data from a nationally representative sample of US adults.Design Cross-section study.Setting The National Health and Nutrition Examination Survey 2007–2012.Participants A total of 13 039 participants aged 20–...
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BMJ Publishing Group
2022-06-01
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| Series: | BMJ Open |
| Online Access: | https://bmjopen.bmj.com/content/12/6/e052320.full |
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| author | Weijie Li Wei Zhang Jie Du |
| author_facet | Weijie Li Wei Zhang Jie Du |
| author_sort | Weijie Li |
| collection | DOAJ |
| description | Objective To investigate the association between dietary carotenoid intake and asthma using data from a nationally representative sample of US adults.Design Cross-section study.Setting The National Health and Nutrition Examination Survey 2007–2012.Participants A total of 13 039 participants aged 20–80 years (current asthma n=1784, non-current asthma n=11 255) were included in this study.Primary and secondary outcome measures Asthma was defined by self-report questionnaires. Weighted logistic regression analyses and the smooth curve fittings were performed to explore the association between total carotenoid intake, dietary carotenoid subgenera, including (α-carotene, β-carotene, β-cryptoxanthin, lutein with zeaxanthin and lycopene) and the risk of asthma.Results The ORs with 95% CIs of dietary α-carotene, dietary β-carotene, dietary β-cryptoxanthin, total lutein with zeaxanthin, total lycopene, dietary carotenoid and total carotenoid intake for individuals with current asthma after adjusting the confounders in model 3 were 0.80 (0.67 to 0.95), 0.67 (0.57 to 0.79), 0.68 (0.55 to 0.85), 0.77 (0.61 to 0.98), 0.71 (0.57 to 0.87), 0.75 (0.59 to 0.96) and 0.61 (0.48 to 0.76) in the highest versus lowest quartile, respectively. The smooth curve fittings suggested a non-linear relationship between total carotenoid intake and the risk of current asthma.Conclusions Higher intake of a-carotene, β-carotene, β-cryptoxanthin, lycopene, lutein with zeaxanthin and total carotenoid were associated with lower odds of having current asthma in the US adults. This is a cross-sectional study and no causal relationship can be drawn, so caution is needed to interpret the results. |
| format | Article |
| id | doaj-art-66fb885d425346d399ca208d55997b31 |
| institution | Kabale University |
| issn | 2044-6055 |
| language | English |
| publishDate | 2022-06-01 |
| publisher | BMJ Publishing Group |
| record_format | Article |
| series | BMJ Open |
| spelling | doaj-art-66fb885d425346d399ca208d55997b312025-02-01T11:45:10ZengBMJ Publishing GroupBMJ Open2044-60552022-06-0112610.1136/bmjopen-2021-052320Association between dietary carotenoid intakes and the risk of asthma in adults: a cross-sectional study of NHANES, 2007–2012Weijie Li0Wei Zhang1Jie Du2Department of Respiratory and Critical Care Medicine, Shaanxi Provincial People`s Hospital, Xi`an, ChinaWomen’s Hospital, Zhejiang University School of Medicine, Hangzhou, China4 Department of Neurology, The People`s Hospital of Kaizhou District, Chongqing, Chongqing, ChinaObjective To investigate the association between dietary carotenoid intake and asthma using data from a nationally representative sample of US adults.Design Cross-section study.Setting The National Health and Nutrition Examination Survey 2007–2012.Participants A total of 13 039 participants aged 20–80 years (current asthma n=1784, non-current asthma n=11 255) were included in this study.Primary and secondary outcome measures Asthma was defined by self-report questionnaires. Weighted logistic regression analyses and the smooth curve fittings were performed to explore the association between total carotenoid intake, dietary carotenoid subgenera, including (α-carotene, β-carotene, β-cryptoxanthin, lutein with zeaxanthin and lycopene) and the risk of asthma.Results The ORs with 95% CIs of dietary α-carotene, dietary β-carotene, dietary β-cryptoxanthin, total lutein with zeaxanthin, total lycopene, dietary carotenoid and total carotenoid intake for individuals with current asthma after adjusting the confounders in model 3 were 0.80 (0.67 to 0.95), 0.67 (0.57 to 0.79), 0.68 (0.55 to 0.85), 0.77 (0.61 to 0.98), 0.71 (0.57 to 0.87), 0.75 (0.59 to 0.96) and 0.61 (0.48 to 0.76) in the highest versus lowest quartile, respectively. The smooth curve fittings suggested a non-linear relationship between total carotenoid intake and the risk of current asthma.Conclusions Higher intake of a-carotene, β-carotene, β-cryptoxanthin, lycopene, lutein with zeaxanthin and total carotenoid were associated with lower odds of having current asthma in the US adults. This is a cross-sectional study and no causal relationship can be drawn, so caution is needed to interpret the results.https://bmjopen.bmj.com/content/12/6/e052320.full |
| spellingShingle | Weijie Li Wei Zhang Jie Du Association between dietary carotenoid intakes and the risk of asthma in adults: a cross-sectional study of NHANES, 2007–2012 BMJ Open |
| title | Association between dietary carotenoid intakes and the risk of asthma in adults: a cross-sectional study of NHANES, 2007–2012 |
| title_full | Association between dietary carotenoid intakes and the risk of asthma in adults: a cross-sectional study of NHANES, 2007–2012 |
| title_fullStr | Association between dietary carotenoid intakes and the risk of asthma in adults: a cross-sectional study of NHANES, 2007–2012 |
| title_full_unstemmed | Association between dietary carotenoid intakes and the risk of asthma in adults: a cross-sectional study of NHANES, 2007–2012 |
| title_short | Association between dietary carotenoid intakes and the risk of asthma in adults: a cross-sectional study of NHANES, 2007–2012 |
| title_sort | association between dietary carotenoid intakes and the risk of asthma in adults a cross sectional study of nhanes 2007 2012 |
| url | https://bmjopen.bmj.com/content/12/6/e052320.full |
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