Global stability of an age-structured virus dynamics model with Beddington-DeAngelis infection function
In this paper, we study an age-structured virus dynamics model with Beddington-DeAngelis infection function. An explicit formula for the basic reproductive number $\mathcal{R}_{0}$ of the model is obtained. We investigate the global behavior of the model in terms of $\mathcal{R}_{0}$: if $\mathcal{R...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
AIMS Press
2015-03-01
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| Series: | Mathematical Biosciences and Engineering |
| Subjects: | |
| Online Access: | https://www.aimspress.com/article/doi/10.3934/mbe.2015.12.859 |
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| Summary: | In this paper, we study an age-structured virus dynamics model with Beddington-DeAngelis infection function. An explicit formula for the basic reproductive number $\mathcal{R}_{0}$ of the model is obtained. We investigate the global behavior of the model in terms of $\mathcal{R}_{0}$: if $\mathcal{R}_{0}\leq1$, then the infection-free equilibrium is globally asymptotically stable, whereas if $\mathcal{R}_{0}>1$, then the infection equilibrium is globally asymptotically stable. Finally, some special cases, which reduce to some known HIV infection models studied by other researchers, are considered. |
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| ISSN: | 1551-0018 |