Rhino-Orbito-Cerebral Mucormycosis: Two Cases with Amaurosis as Presentation, Medical Surgical Management and Follow-Up

Purpose: Mucormycosis is an infection caused by fungi to the class Zygomycetes that usually appears in immunosuppressed patients. Diagnostic confirmation is often delayed, with fatal prognosis in cases in which treatment is not rapidly established. Case report: We present two clinical cases of rhino...

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Main Authors: Carmen Navarro-Perea, Ignacio Cañas-Zamarra, Enrique Mencía-Gutiérrez, Enrique Revilla-Sánchez, María-Dolores Lago-Llinás, Silvia Pérez-Trigo, Álvaro Bengoa-González
Format: Article
Language:English
Published: Wiley 2019-01-01
Series:Case Reports in Ophthalmological Medicine
Online Access:http://dx.doi.org/10.1155/2019/4215989
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author Carmen Navarro-Perea
Ignacio Cañas-Zamarra
Enrique Mencía-Gutiérrez
Enrique Revilla-Sánchez
María-Dolores Lago-Llinás
Silvia Pérez-Trigo
Álvaro Bengoa-González
author_facet Carmen Navarro-Perea
Ignacio Cañas-Zamarra
Enrique Mencía-Gutiérrez
Enrique Revilla-Sánchez
María-Dolores Lago-Llinás
Silvia Pérez-Trigo
Álvaro Bengoa-González
author_sort Carmen Navarro-Perea
collection DOAJ
description Purpose: Mucormycosis is an infection caused by fungi to the class Zygomycetes that usually appears in immunosuppressed patients. Diagnostic confirmation is often delayed, with fatal prognosis in cases in which treatment is not rapidly established. Case report: We present two clinical cases of rhino-orbito-cerebral mucormycosis with an atypical presentation form, consisting of a unilateral complete sudden vision loss. Intravenous treatment with liposomal amphotericin B was started and total orbital exenteration surgery was performed. The removed surgical area was filled with gauze impregnated with liposomal amphotericin B and was left open for cures every 12 hours. Due to the good clinical evolution, a reconstruction of the orbital exenteration defect was performed in Case 1 with a temporal muscle flap and a skin island pedicled flap. In Case 2, reconstruction was not performed due to the poor evolution of the patient. Discussion: As it is a very aggressive surgery, the aesthetic and functional sequelae are very important. When the survival of the patient is achieved, we should offer reconstructive solutions that improve their quality of life. The reconstruction carried out using a flap of the temporal muscle can be made in a single act without requiring microvascular surgery.
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institution Kabale University
issn 2090-6722
2090-6730
language English
publishDate 2019-01-01
publisher Wiley
record_format Article
series Case Reports in Ophthalmological Medicine
spelling doaj-art-66f0ad470d8843f7b4bd1f23e8c7f60b2025-02-03T01:10:40ZengWileyCase Reports in Ophthalmological Medicine2090-67222090-67302019-01-01201910.1155/2019/42159894215989Rhino-Orbito-Cerebral Mucormycosis: Two Cases with Amaurosis as Presentation, Medical Surgical Management and Follow-UpCarmen Navarro-Perea0Ignacio Cañas-Zamarra1Enrique Mencía-Gutiérrez2Enrique Revilla-Sánchez3María-Dolores Lago-Llinás4Silvia Pérez-Trigo5Álvaro Bengoa-González6Ophthalmology Department, 12 de Octubre Hospital, Complutense University, 28041 Madrid, SpainOphthalmology Department, 12 de Octubre Hospital, Complutense University, 28041 Madrid, SpainOphthalmology Department, 12 de Octubre Hospital, Complutense University, 28041 Madrid, SpainPathology Department, 12 de Octubre Hospital, Complutense University, 28041 Madrid, SpainOphthalmology Department, 12 de Octubre Hospital, Complutense University, 28041 Madrid, SpainOphthalmology Department, 12 de Octubre Hospital, Complutense University, 28041 Madrid, SpainOphthalmology Department, 12 de Octubre Hospital, Complutense University, 28041 Madrid, SpainPurpose: Mucormycosis is an infection caused by fungi to the class Zygomycetes that usually appears in immunosuppressed patients. Diagnostic confirmation is often delayed, with fatal prognosis in cases in which treatment is not rapidly established. Case report: We present two clinical cases of rhino-orbito-cerebral mucormycosis with an atypical presentation form, consisting of a unilateral complete sudden vision loss. Intravenous treatment with liposomal amphotericin B was started and total orbital exenteration surgery was performed. The removed surgical area was filled with gauze impregnated with liposomal amphotericin B and was left open for cures every 12 hours. Due to the good clinical evolution, a reconstruction of the orbital exenteration defect was performed in Case 1 with a temporal muscle flap and a skin island pedicled flap. In Case 2, reconstruction was not performed due to the poor evolution of the patient. Discussion: As it is a very aggressive surgery, the aesthetic and functional sequelae are very important. When the survival of the patient is achieved, we should offer reconstructive solutions that improve their quality of life. The reconstruction carried out using a flap of the temporal muscle can be made in a single act without requiring microvascular surgery.http://dx.doi.org/10.1155/2019/4215989
spellingShingle Carmen Navarro-Perea
Ignacio Cañas-Zamarra
Enrique Mencía-Gutiérrez
Enrique Revilla-Sánchez
María-Dolores Lago-Llinás
Silvia Pérez-Trigo
Álvaro Bengoa-González
Rhino-Orbito-Cerebral Mucormycosis: Two Cases with Amaurosis as Presentation, Medical Surgical Management and Follow-Up
Case Reports in Ophthalmological Medicine
title Rhino-Orbito-Cerebral Mucormycosis: Two Cases with Amaurosis as Presentation, Medical Surgical Management and Follow-Up
title_full Rhino-Orbito-Cerebral Mucormycosis: Two Cases with Amaurosis as Presentation, Medical Surgical Management and Follow-Up
title_fullStr Rhino-Orbito-Cerebral Mucormycosis: Two Cases with Amaurosis as Presentation, Medical Surgical Management and Follow-Up
title_full_unstemmed Rhino-Orbito-Cerebral Mucormycosis: Two Cases with Amaurosis as Presentation, Medical Surgical Management and Follow-Up
title_short Rhino-Orbito-Cerebral Mucormycosis: Two Cases with Amaurosis as Presentation, Medical Surgical Management and Follow-Up
title_sort rhino orbito cerebral mucormycosis two cases with amaurosis as presentation medical surgical management and follow up
url http://dx.doi.org/10.1155/2019/4215989
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