Rhino-Orbito-Cerebral Mucormycosis: Two Cases with Amaurosis as Presentation, Medical Surgical Management and Follow-Up
Purpose: Mucormycosis is an infection caused by fungi to the class Zygomycetes that usually appears in immunosuppressed patients. Diagnostic confirmation is often delayed, with fatal prognosis in cases in which treatment is not rapidly established. Case report: We present two clinical cases of rhino...
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Language: | English |
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Wiley
2019-01-01
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Series: | Case Reports in Ophthalmological Medicine |
Online Access: | http://dx.doi.org/10.1155/2019/4215989 |
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author | Carmen Navarro-Perea Ignacio Cañas-Zamarra Enrique Mencía-Gutiérrez Enrique Revilla-Sánchez María-Dolores Lago-Llinás Silvia Pérez-Trigo Álvaro Bengoa-González |
author_facet | Carmen Navarro-Perea Ignacio Cañas-Zamarra Enrique Mencía-Gutiérrez Enrique Revilla-Sánchez María-Dolores Lago-Llinás Silvia Pérez-Trigo Álvaro Bengoa-González |
author_sort | Carmen Navarro-Perea |
collection | DOAJ |
description | Purpose: Mucormycosis is an infection caused by fungi to the class Zygomycetes that usually appears in immunosuppressed patients. Diagnostic confirmation is often delayed, with fatal prognosis in cases in which treatment is not rapidly established. Case report: We present two clinical cases of rhino-orbito-cerebral mucormycosis with an atypical presentation form, consisting of a unilateral complete sudden vision loss. Intravenous treatment with liposomal amphotericin B was started and total orbital exenteration surgery was performed. The removed surgical area was filled with gauze impregnated with liposomal amphotericin B and was left open for cures every 12 hours. Due to the good clinical evolution, a reconstruction of the orbital exenteration defect was performed in Case 1 with a temporal muscle flap and a skin island pedicled flap. In Case 2, reconstruction was not performed due to the poor evolution of the patient. Discussion: As it is a very aggressive surgery, the aesthetic and functional sequelae are very important. When the survival of the patient is achieved, we should offer reconstructive solutions that improve their quality of life. The reconstruction carried out using a flap of the temporal muscle can be made in a single act without requiring microvascular surgery. |
format | Article |
id | doaj-art-66f0ad470d8843f7b4bd1f23e8c7f60b |
institution | Kabale University |
issn | 2090-6722 2090-6730 |
language | English |
publishDate | 2019-01-01 |
publisher | Wiley |
record_format | Article |
series | Case Reports in Ophthalmological Medicine |
spelling | doaj-art-66f0ad470d8843f7b4bd1f23e8c7f60b2025-02-03T01:10:40ZengWileyCase Reports in Ophthalmological Medicine2090-67222090-67302019-01-01201910.1155/2019/42159894215989Rhino-Orbito-Cerebral Mucormycosis: Two Cases with Amaurosis as Presentation, Medical Surgical Management and Follow-UpCarmen Navarro-Perea0Ignacio Cañas-Zamarra1Enrique Mencía-Gutiérrez2Enrique Revilla-Sánchez3María-Dolores Lago-Llinás4Silvia Pérez-Trigo5Álvaro Bengoa-González6Ophthalmology Department, 12 de Octubre Hospital, Complutense University, 28041 Madrid, SpainOphthalmology Department, 12 de Octubre Hospital, Complutense University, 28041 Madrid, SpainOphthalmology Department, 12 de Octubre Hospital, Complutense University, 28041 Madrid, SpainPathology Department, 12 de Octubre Hospital, Complutense University, 28041 Madrid, SpainOphthalmology Department, 12 de Octubre Hospital, Complutense University, 28041 Madrid, SpainOphthalmology Department, 12 de Octubre Hospital, Complutense University, 28041 Madrid, SpainOphthalmology Department, 12 de Octubre Hospital, Complutense University, 28041 Madrid, SpainPurpose: Mucormycosis is an infection caused by fungi to the class Zygomycetes that usually appears in immunosuppressed patients. Diagnostic confirmation is often delayed, with fatal prognosis in cases in which treatment is not rapidly established. Case report: We present two clinical cases of rhino-orbito-cerebral mucormycosis with an atypical presentation form, consisting of a unilateral complete sudden vision loss. Intravenous treatment with liposomal amphotericin B was started and total orbital exenteration surgery was performed. The removed surgical area was filled with gauze impregnated with liposomal amphotericin B and was left open for cures every 12 hours. Due to the good clinical evolution, a reconstruction of the orbital exenteration defect was performed in Case 1 with a temporal muscle flap and a skin island pedicled flap. In Case 2, reconstruction was not performed due to the poor evolution of the patient. Discussion: As it is a very aggressive surgery, the aesthetic and functional sequelae are very important. When the survival of the patient is achieved, we should offer reconstructive solutions that improve their quality of life. The reconstruction carried out using a flap of the temporal muscle can be made in a single act without requiring microvascular surgery.http://dx.doi.org/10.1155/2019/4215989 |
spellingShingle | Carmen Navarro-Perea Ignacio Cañas-Zamarra Enrique Mencía-Gutiérrez Enrique Revilla-Sánchez María-Dolores Lago-Llinás Silvia Pérez-Trigo Álvaro Bengoa-González Rhino-Orbito-Cerebral Mucormycosis: Two Cases with Amaurosis as Presentation, Medical Surgical Management and Follow-Up Case Reports in Ophthalmological Medicine |
title | Rhino-Orbito-Cerebral Mucormycosis: Two Cases with Amaurosis as Presentation, Medical Surgical Management and Follow-Up |
title_full | Rhino-Orbito-Cerebral Mucormycosis: Two Cases with Amaurosis as Presentation, Medical Surgical Management and Follow-Up |
title_fullStr | Rhino-Orbito-Cerebral Mucormycosis: Two Cases with Amaurosis as Presentation, Medical Surgical Management and Follow-Up |
title_full_unstemmed | Rhino-Orbito-Cerebral Mucormycosis: Two Cases with Amaurosis as Presentation, Medical Surgical Management and Follow-Up |
title_short | Rhino-Orbito-Cerebral Mucormycosis: Two Cases with Amaurosis as Presentation, Medical Surgical Management and Follow-Up |
title_sort | rhino orbito cerebral mucormycosis two cases with amaurosis as presentation medical surgical management and follow up |
url | http://dx.doi.org/10.1155/2019/4215989 |
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