Entamoeba gingivalis in Acute Osteomyelitis of the Mandible

An 86-year-old woman presented with osteonecrosis of the mandible following bisphosphonate therapy for multiple myeloma, and underwent surgical debridement and multiple dental extractions. Histopathologic examination of the necrotic bone fragments revealed acute osteomyelitis with mixed flora and or...

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Main Authors: Feriyl Bhaijee, Diana Bell
Format: Article
Language:English
Published: Wiley 2011-01-01
Series:Case Reports in Medicine
Online Access:http://dx.doi.org/10.1155/2011/357301
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author Feriyl Bhaijee
Diana Bell
author_facet Feriyl Bhaijee
Diana Bell
author_sort Feriyl Bhaijee
collection DOAJ
description An 86-year-old woman presented with osteonecrosis of the mandible following bisphosphonate therapy for multiple myeloma, and underwent surgical debridement and multiple dental extractions. Histopathologic examination of the necrotic bone fragments revealed acute osteomyelitis with mixed flora and organisms morphologically consistent with Entamoeba gingivalis. In addition to oral scrapings and sputum, E. gingivalis has been identified in specimens obtained from the uterus, cervix, neck lymph nodes, and lung. It is rarely found in lesions of the head and neck. We present an unusual case of E. gingivalis in acute osteomyelitis of the mandible, following bisphosphonate therapy for multiple myeloma. To our knowledge, this is the first reported case of E. gingivalis in association with osteomyelitis.
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spelling doaj-art-66e82801aea8454f83e3a789f53a9ad02025-02-03T06:06:10ZengWileyCase Reports in Medicine1687-96271687-96352011-01-01201110.1155/2011/357301357301Entamoeba gingivalis in Acute Osteomyelitis of the MandibleFeriyl Bhaijee0Diana Bell1University of Mississippi Medical Center, 2500 North State Street, Jackson, MS 39216, USADepartment of Pathology, MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USAAn 86-year-old woman presented with osteonecrosis of the mandible following bisphosphonate therapy for multiple myeloma, and underwent surgical debridement and multiple dental extractions. Histopathologic examination of the necrotic bone fragments revealed acute osteomyelitis with mixed flora and organisms morphologically consistent with Entamoeba gingivalis. In addition to oral scrapings and sputum, E. gingivalis has been identified in specimens obtained from the uterus, cervix, neck lymph nodes, and lung. It is rarely found in lesions of the head and neck. We present an unusual case of E. gingivalis in acute osteomyelitis of the mandible, following bisphosphonate therapy for multiple myeloma. To our knowledge, this is the first reported case of E. gingivalis in association with osteomyelitis.http://dx.doi.org/10.1155/2011/357301
spellingShingle Feriyl Bhaijee
Diana Bell
Entamoeba gingivalis in Acute Osteomyelitis of the Mandible
Case Reports in Medicine
title Entamoeba gingivalis in Acute Osteomyelitis of the Mandible
title_full Entamoeba gingivalis in Acute Osteomyelitis of the Mandible
title_fullStr Entamoeba gingivalis in Acute Osteomyelitis of the Mandible
title_full_unstemmed Entamoeba gingivalis in Acute Osteomyelitis of the Mandible
title_short Entamoeba gingivalis in Acute Osteomyelitis of the Mandible
title_sort entamoeba gingivalis in acute osteomyelitis of the mandible
url http://dx.doi.org/10.1155/2011/357301
work_keys_str_mv AT feriylbhaijee entamoebagingivalisinacuteosteomyelitisofthemandible
AT dianabell entamoebagingivalisinacuteosteomyelitisofthemandible