Advanced imaging techniques in crystal arthritis
Gout and calcium pyrophosphate deposition (CPPD) disease are the most common causes of crystal arthritis. Identifying the pathogenic crystal deposition is the cornerstone of the diagnosis, but also prognosis and monitoring of the diseases. Conventional radiography has been for decades the only imagi...
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| Format: | Article |
| Language: | English |
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SAGE Publishing
2025-02-01
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| Series: | Therapeutic Advances in Musculoskeletal Disease |
| Online Access: | https://doi.org/10.1177/1759720X251316097 |
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| author | Victor Laurent Georgios Filippou Silvia Sirotti Tristan Pascart |
| author_facet | Victor Laurent Georgios Filippou Silvia Sirotti Tristan Pascart |
| author_sort | Victor Laurent |
| collection | DOAJ |
| description | Gout and calcium pyrophosphate deposition (CPPD) disease are the most common causes of crystal arthritis. Identifying the pathogenic crystal deposition is the cornerstone of the diagnosis, but also prognosis and monitoring of the diseases. Conventional radiography has been for decades the only imaging technique used, with its very restricted sensitivity in both diseases. Advanced techniques, namely ultrasound and dual-energy computed tomography (DECT), are being increasingly used in the diagnosis and management of gout and CPPD diseases, and their role is now well recognized in classification criteria and in recommendations for the diagnosis and management. In gout, ultrasound elementary lesions of monosodium urate deposition are well defined and have been shown to be sensitive to change and can be monitored, while direct quantification of these deposits can be performed with DECT. In CPPD disease, the definition of elementary lesions and their scoring has been well established for ultrasound, while the proof of concept that DECT can help discriminate calcium pyrophosphate crystal deposits among other calcium-containing structures has been shown. The aim of this narrative review is to provide an overview of the use of advanced imaging techniques in crystal-induced arthropathies. |
| format | Article |
| id | doaj-art-66de5d7db1644a52b87d862d86a61441 |
| institution | Kabale University |
| issn | 1759-7218 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Therapeutic Advances in Musculoskeletal Disease |
| spelling | doaj-art-66de5d7db1644a52b87d862d86a614412025-02-04T12:03:25ZengSAGE PublishingTherapeutic Advances in Musculoskeletal Disease1759-72182025-02-011710.1177/1759720X251316097Advanced imaging techniques in crystal arthritisVictor LaurentGeorgios FilippouSilvia SirottiTristan PascartGout and calcium pyrophosphate deposition (CPPD) disease are the most common causes of crystal arthritis. Identifying the pathogenic crystal deposition is the cornerstone of the diagnosis, but also prognosis and monitoring of the diseases. Conventional radiography has been for decades the only imaging technique used, with its very restricted sensitivity in both diseases. Advanced techniques, namely ultrasound and dual-energy computed tomography (DECT), are being increasingly used in the diagnosis and management of gout and CPPD diseases, and their role is now well recognized in classification criteria and in recommendations for the diagnosis and management. In gout, ultrasound elementary lesions of monosodium urate deposition are well defined and have been shown to be sensitive to change and can be monitored, while direct quantification of these deposits can be performed with DECT. In CPPD disease, the definition of elementary lesions and their scoring has been well established for ultrasound, while the proof of concept that DECT can help discriminate calcium pyrophosphate crystal deposits among other calcium-containing structures has been shown. The aim of this narrative review is to provide an overview of the use of advanced imaging techniques in crystal-induced arthropathies.https://doi.org/10.1177/1759720X251316097 |
| spellingShingle | Victor Laurent Georgios Filippou Silvia Sirotti Tristan Pascart Advanced imaging techniques in crystal arthritis Therapeutic Advances in Musculoskeletal Disease |
| title | Advanced imaging techniques in crystal arthritis |
| title_full | Advanced imaging techniques in crystal arthritis |
| title_fullStr | Advanced imaging techniques in crystal arthritis |
| title_full_unstemmed | Advanced imaging techniques in crystal arthritis |
| title_short | Advanced imaging techniques in crystal arthritis |
| title_sort | advanced imaging techniques in crystal arthritis |
| url | https://doi.org/10.1177/1759720X251316097 |
| work_keys_str_mv | AT victorlaurent advancedimagingtechniquesincrystalarthritis AT georgiosfilippou advancedimagingtechniquesincrystalarthritis AT silviasirotti advancedimagingtechniquesincrystalarthritis AT tristanpascart advancedimagingtechniquesincrystalarthritis |