Intravenous Lormetazepam during Sedation Weaning in a 26-Year-Old Critically Ill Woman

Recent evidence revealed that sedation is related to adverse outcomes including a higher mortality. Despite this fact, patients sometimes require deep sedation for a limited period of time to control, for example, intracranial hypertension. In particular in these cases, weaning from sedation is ofte...

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Main Authors: Alawi Luetz, Bjoern Weiss, Claudia D. Spies
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:Case Reports in Critical Care
Online Access:http://dx.doi.org/10.1155/2014/372740
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author Alawi Luetz
Bjoern Weiss
Claudia D. Spies
author_facet Alawi Luetz
Bjoern Weiss
Claudia D. Spies
author_sort Alawi Luetz
collection DOAJ
description Recent evidence revealed that sedation is related to adverse outcomes including a higher mortality. Despite this fact, patients sometimes require deep sedation for a limited period of time to control, for example, intracranial hypertension. In particular in these cases, weaning from sedation is often challenging due to emerging agitation, stress, and delirium. The submitted research letter reports a rare case of severe and persisting agitation that was unresponsive to all available treatments. Ultimately, lormetazepam which has recently become available for intravenous use in Germany resolved the problem by stress-reduction and anxiolysis without leading to measurable sedation.
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institution Kabale University
issn 2090-6420
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spelling doaj-art-66d0765979674692b787abc3079b8c272025-02-03T01:10:28ZengWileyCase Reports in Critical Care2090-64202090-64392014-01-01201410.1155/2014/372740372740Intravenous Lormetazepam during Sedation Weaning in a 26-Year-Old Critically Ill WomanAlawi Luetz0Bjoern Weiss1Claudia D. Spies2Department of Anesthesiology and Intensive Care Medicine, Charité-Universitätsmedizin Berlin, Campus Charité Mitte and Campus Virchow-Klinikum, Augustenburger Platz 1, 13353 Berlin, GermanyDepartment of Anesthesiology and Intensive Care Medicine, Charité-Universitätsmedizin Berlin, Campus Charité Mitte and Campus Virchow-Klinikum, Augustenburger Platz 1, 13353 Berlin, GermanyDepartment of Anesthesiology and Intensive Care Medicine, Charité-Universitätsmedizin Berlin, Campus Charité Mitte and Campus Virchow-Klinikum, Augustenburger Platz 1, 13353 Berlin, GermanyRecent evidence revealed that sedation is related to adverse outcomes including a higher mortality. Despite this fact, patients sometimes require deep sedation for a limited period of time to control, for example, intracranial hypertension. In particular in these cases, weaning from sedation is often challenging due to emerging agitation, stress, and delirium. The submitted research letter reports a rare case of severe and persisting agitation that was unresponsive to all available treatments. Ultimately, lormetazepam which has recently become available for intravenous use in Germany resolved the problem by stress-reduction and anxiolysis without leading to measurable sedation.http://dx.doi.org/10.1155/2014/372740
spellingShingle Alawi Luetz
Bjoern Weiss
Claudia D. Spies
Intravenous Lormetazepam during Sedation Weaning in a 26-Year-Old Critically Ill Woman
Case Reports in Critical Care
title Intravenous Lormetazepam during Sedation Weaning in a 26-Year-Old Critically Ill Woman
title_full Intravenous Lormetazepam during Sedation Weaning in a 26-Year-Old Critically Ill Woman
title_fullStr Intravenous Lormetazepam during Sedation Weaning in a 26-Year-Old Critically Ill Woman
title_full_unstemmed Intravenous Lormetazepam during Sedation Weaning in a 26-Year-Old Critically Ill Woman
title_short Intravenous Lormetazepam during Sedation Weaning in a 26-Year-Old Critically Ill Woman
title_sort intravenous lormetazepam during sedation weaning in a 26 year old critically ill woman
url http://dx.doi.org/10.1155/2014/372740
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AT bjoernweiss intravenouslormetazepamduringsedationweaningina26yearoldcriticallyillwoman
AT claudiadspies intravenouslormetazepamduringsedationweaningina26yearoldcriticallyillwoman