Unusual Presentation of a Colonic Sarcoidosis
Sarcoidosis is a multisystemic disorder of unknown cause that affects almost every tissue in the body. Colon is an extremely rare location of this disease. Clinical presentation, endoscopic appearances, and radiologic findings are not specific and may mimic much other affection. We report the case o...
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2012-01-01
|
| Series: | Case Reports in Medicine |
| Online Access: | http://dx.doi.org/10.1155/2012/169760 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832546198949462016 |
|---|---|
| author | Sami Daldoul Wissem Triki Kaouther El Jeri Abdeljelil Zaouche |
| author_facet | Sami Daldoul Wissem Triki Kaouther El Jeri Abdeljelil Zaouche |
| author_sort | Sami Daldoul |
| collection | DOAJ |
| description | Sarcoidosis is a multisystemic disorder of unknown cause that affects almost every tissue in the body. Colon is an extremely rare location of this disease. Clinical presentation, endoscopic appearances, and radiologic findings are not specific and may mimic much other affection. We report the case of a 64-year-old woman with inactive pulmonary sarcoidosis who presented alternating constipation and diarrhea. Colonoscopy revealed a stenotic tumor in the ascending colon. Histology failed to determine the nature of the lesion. Radiologic findings are those of a long stenotic tumor of the ascending colon associated with a multiple satellite lymphadenopathy. Endoscopic and radiologic descriptions are highly suggestive of a malignancy. The patient underwent a laparotomy, and a right hemicolectomy was performed. Examination of the resected specimen showed follicular structure with central epitheloid and giant cells and surrounding fibroblasts. These findings made the diagnosis of colonic sarcoidosis. The nonspecificity of the endoscopic and radiological signs of gastrointestinal sarcoidosis and the extreme rarity of colonic location make the preoperative diagnosis unlikely. The diagnosis will be then made only on histological examination of surgical specimens. We describe, through this observation, the results of paraclinical investigations that can suggest diagnosis and perhaps avoid surgery. |
| format | Article |
| id | doaj-art-66ccdd6127754143ac14bcc013b86c5d |
| institution | Kabale University |
| issn | 1687-9627 1687-9635 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Medicine |
| spelling | doaj-art-66ccdd6127754143ac14bcc013b86c5d2025-02-03T07:23:34ZengWileyCase Reports in Medicine1687-96271687-96352012-01-01201210.1155/2012/169760169760Unusual Presentation of a Colonic SarcoidosisSami Daldoul0Wissem Triki1Kaouther El Jeri2Abdeljelil Zaouche3Department A of General Surgery, Charles-Nicole’s Hospital, Boulevard 9-avril-1938, Tunis 1006, TunisiaDepartment A of General Surgery, Charles-Nicole’s Hospital, Boulevard 9-avril-1938, Tunis 1006, TunisiaDepartment of Hepatology and Gastroenterology, Charles-Nicole’s Hospital, Boulevard 9-avril-1938, Tunis 1006, TunisiaDepartment A of General Surgery, Charles-Nicole’s Hospital, Boulevard 9-avril-1938, Tunis 1006, TunisiaSarcoidosis is a multisystemic disorder of unknown cause that affects almost every tissue in the body. Colon is an extremely rare location of this disease. Clinical presentation, endoscopic appearances, and radiologic findings are not specific and may mimic much other affection. We report the case of a 64-year-old woman with inactive pulmonary sarcoidosis who presented alternating constipation and diarrhea. Colonoscopy revealed a stenotic tumor in the ascending colon. Histology failed to determine the nature of the lesion. Radiologic findings are those of a long stenotic tumor of the ascending colon associated with a multiple satellite lymphadenopathy. Endoscopic and radiologic descriptions are highly suggestive of a malignancy. The patient underwent a laparotomy, and a right hemicolectomy was performed. Examination of the resected specimen showed follicular structure with central epitheloid and giant cells and surrounding fibroblasts. These findings made the diagnosis of colonic sarcoidosis. The nonspecificity of the endoscopic and radiological signs of gastrointestinal sarcoidosis and the extreme rarity of colonic location make the preoperative diagnosis unlikely. The diagnosis will be then made only on histological examination of surgical specimens. We describe, through this observation, the results of paraclinical investigations that can suggest diagnosis and perhaps avoid surgery.http://dx.doi.org/10.1155/2012/169760 |
| spellingShingle | Sami Daldoul Wissem Triki Kaouther El Jeri Abdeljelil Zaouche Unusual Presentation of a Colonic Sarcoidosis Case Reports in Medicine |
| title | Unusual Presentation of a Colonic Sarcoidosis |
| title_full | Unusual Presentation of a Colonic Sarcoidosis |
| title_fullStr | Unusual Presentation of a Colonic Sarcoidosis |
| title_full_unstemmed | Unusual Presentation of a Colonic Sarcoidosis |
| title_short | Unusual Presentation of a Colonic Sarcoidosis |
| title_sort | unusual presentation of a colonic sarcoidosis |
| url | http://dx.doi.org/10.1155/2012/169760 |
| work_keys_str_mv | AT samidaldoul unusualpresentationofacolonicsarcoidosis AT wissemtriki unusualpresentationofacolonicsarcoidosis AT kaouthereljeri unusualpresentationofacolonicsarcoidosis AT abdeljelilzaouche unusualpresentationofacolonicsarcoidosis |