Cyclic di AMP phosphodiesterase nanovaccine elicits protective immunity against Burkholderia cenocepacia infection in mice

Cyclic di AMP phosphodiesterase nanovaccine elicits protective immunity against Burkholderia cenocepacia infection in mice

Abstract Burkholderia cenocepacia causes life-threatening infections in immunocompromised patients. Treatment is challenging due to intrinsic antibiotic multiresistance, so vaccination provides an alternative approach. We aimed to identify vaccine candidates using reverse vaccinology and evaluate th...

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Bibliographic Details
Main Authors: Wesam E. Gawad, Yosra I. Nagy, Tamer M. Samir, Ahmed Mohamed Ibrahim Mansour, Omneya M. Helmy
Format: Article
Language:English
Published: Nature Portfolio 2025-02-01
Series:npj Vaccines
Online Access:https://doi.org/10.1038/s41541-025-01074-4
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