Reliability of Endoscopic Ultrasound Using Miniprobes and Grayscale Histogram Analysis in Diagnosing Upper Gastrointestinal Subepithelial Lesions
Background. To assess the role of endoscopic ultrasound (EUS) in the diagnosis of upper gastrointestinal subepithelial lesions (SELs) and to investigate EUS combined with a grayscale histogram analysis for the differentiation of leiomyomas and gastrointestinal stromal tumors (GISTs). Methods. A retr...
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| Format: | Article |
| Language: | English |
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Wiley
2020-01-01
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| Series: | Gastroenterology Research and Practice |
| Online Access: | http://dx.doi.org/10.1155/2020/6591341 |
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| author | Samiullah Khan Rui Zhang Weili Fang Tao Wang Shu Li Danna Wang Yixiang Chang Lanping Zhu Bang-mao Wang Wentian Liu |
| author_facet | Samiullah Khan Rui Zhang Weili Fang Tao Wang Shu Li Danna Wang Yixiang Chang Lanping Zhu Bang-mao Wang Wentian Liu |
| author_sort | Samiullah Khan |
| collection | DOAJ |
| description | Background. To assess the role of endoscopic ultrasound (EUS) in the diagnosis of upper gastrointestinal subepithelial lesions (SELs) and to investigate EUS combined with a grayscale histogram analysis for the differentiation of leiomyomas and gastrointestinal stromal tumors (GISTs). Methods. A retrospective study of 709 patients with upper gastrointestinal SELs was conducted by EUS before endoscopic resection. The EUS findings of SELs and pathological results after endoscopic resection were compared. The EUS images of SELs, particularly, leiomyoma and GIST, were further analyzed via a grayscale histogram to differentiate between the two tumors. Results. Of the 709 patients, 47 cases were pathologically undetermined. The diagnostic consistency of EUS with endoscopic resection was 88.2% (584/662), including 185 muscularis mucosa, 61 submucosa, and 338 muscularis propria, respectively. The diagnostic consistency of EUS with pathology was 80.1% (530/662). The gray value of GISTs was significantly higher than that of leiomyomas (58.9±8.3 vs. 39.5±5.9, t=57.0, P<0.0001). The standard deviation of leiomyomas was significantly lower than that of GISTs (20.6±7.0 vs. 39.8±9.3, t=23.7, P<0.0001). The grayscale histogram analysis of GISTs showed higher echo ultrasound, and the echo of leiomyoma was more uniform. Conclusion. EUS is the preferred procedure for the evaluation of upper gastrointestinal SELs. EUS combined with a grayscale histogram analysis is an effective method for the differentiation of leiomyomas and GISTs. |
| format | Article |
| id | doaj-art-66c04301f43b4642b993380f517bc8e7 |
| institution | Kabale University |
| issn | 1687-6121 1687-630X |
| language | English |
| publishDate | 2020-01-01 |
| publisher | Wiley |
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| series | Gastroenterology Research and Practice |
| spelling | doaj-art-66c04301f43b4642b993380f517bc8e72025-02-03T01:05:04ZengWileyGastroenterology Research and Practice1687-61211687-630X2020-01-01202010.1155/2020/65913416591341Reliability of Endoscopic Ultrasound Using Miniprobes and Grayscale Histogram Analysis in Diagnosing Upper Gastrointestinal Subepithelial LesionsSamiullah Khan0Rui Zhang1Weili Fang2Tao Wang3Shu Li4Danna Wang5Yixiang Chang6Lanping Zhu7Bang-mao Wang8Wentian Liu9Department of Gastroenterology and Hepatology, Tianjin Medical University General Hospital, Tianjin., ChinaDepartment of Gastroenterology and Hepatology, Tianjin Medical University General Hospital, Tianjin., ChinaDepartment of Gastroenterology and Hepatology, Tianjin Medical University General Hospital, Tianjin., ChinaDepartment of Gastroenterology and Hepatology, Tianjin Medical University General Hospital, Tianjin., ChinaDepartment of Gastroenterology and Hepatology, Tianjin Medical University General Hospital, Tianjin., ChinaDepartment of Gastroenterology and Hepatology, Tianjin Medical University General Hospital, Tianjin., ChinaDepartment of Gastroenterology and Hepatology, Tianjin Medical University General Hospital, Tianjin., ChinaDepartment of Gastroenterology and Hepatology, Tianjin Medical University General Hospital, Tianjin., ChinaDepartment of Gastroenterology and Hepatology, Tianjin Medical University General Hospital, Tianjin., ChinaDepartment of Gastroenterology and Hepatology, Tianjin Medical University General Hospital, Tianjin., ChinaBackground. To assess the role of endoscopic ultrasound (EUS) in the diagnosis of upper gastrointestinal subepithelial lesions (SELs) and to investigate EUS combined with a grayscale histogram analysis for the differentiation of leiomyomas and gastrointestinal stromal tumors (GISTs). Methods. A retrospective study of 709 patients with upper gastrointestinal SELs was conducted by EUS before endoscopic resection. The EUS findings of SELs and pathological results after endoscopic resection were compared. The EUS images of SELs, particularly, leiomyoma and GIST, were further analyzed via a grayscale histogram to differentiate between the two tumors. Results. Of the 709 patients, 47 cases were pathologically undetermined. The diagnostic consistency of EUS with endoscopic resection was 88.2% (584/662), including 185 muscularis mucosa, 61 submucosa, and 338 muscularis propria, respectively. The diagnostic consistency of EUS with pathology was 80.1% (530/662). The gray value of GISTs was significantly higher than that of leiomyomas (58.9±8.3 vs. 39.5±5.9, t=57.0, P<0.0001). The standard deviation of leiomyomas was significantly lower than that of GISTs (20.6±7.0 vs. 39.8±9.3, t=23.7, P<0.0001). The grayscale histogram analysis of GISTs showed higher echo ultrasound, and the echo of leiomyoma was more uniform. Conclusion. EUS is the preferred procedure for the evaluation of upper gastrointestinal SELs. EUS combined with a grayscale histogram analysis is an effective method for the differentiation of leiomyomas and GISTs.http://dx.doi.org/10.1155/2020/6591341 |
| spellingShingle | Samiullah Khan Rui Zhang Weili Fang Tao Wang Shu Li Danna Wang Yixiang Chang Lanping Zhu Bang-mao Wang Wentian Liu Reliability of Endoscopic Ultrasound Using Miniprobes and Grayscale Histogram Analysis in Diagnosing Upper Gastrointestinal Subepithelial Lesions Gastroenterology Research and Practice |
| title | Reliability of Endoscopic Ultrasound Using Miniprobes and Grayscale Histogram Analysis in Diagnosing Upper Gastrointestinal Subepithelial Lesions |
| title_full | Reliability of Endoscopic Ultrasound Using Miniprobes and Grayscale Histogram Analysis in Diagnosing Upper Gastrointestinal Subepithelial Lesions |
| title_fullStr | Reliability of Endoscopic Ultrasound Using Miniprobes and Grayscale Histogram Analysis in Diagnosing Upper Gastrointestinal Subepithelial Lesions |
| title_full_unstemmed | Reliability of Endoscopic Ultrasound Using Miniprobes and Grayscale Histogram Analysis in Diagnosing Upper Gastrointestinal Subepithelial Lesions |
| title_short | Reliability of Endoscopic Ultrasound Using Miniprobes and Grayscale Histogram Analysis in Diagnosing Upper Gastrointestinal Subepithelial Lesions |
| title_sort | reliability of endoscopic ultrasound using miniprobes and grayscale histogram analysis in diagnosing upper gastrointestinal subepithelial lesions |
| url | http://dx.doi.org/10.1155/2020/6591341 |
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