Asymptotic Properties of a Hepatitis B Virus Infection Model with Time Delay

A hepatitis B virus infection model with time delay is discussed. By analyzing the corresponding characteristic equations, the local stability of each of the feasible equilibria of the model is studied. By using comparison arguments, it is proved that if the basic reproduction ratio is less than uni...

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Main Authors: Xiaohong Tian, Rui Xu
Format: Article
Language:English
Published: Wiley 2010-01-01
Series:Discrete Dynamics in Nature and Society
Online Access:http://dx.doi.org/10.1155/2010/182340
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author Xiaohong Tian
Rui Xu
author_facet Xiaohong Tian
Rui Xu
author_sort Xiaohong Tian
collection DOAJ
description A hepatitis B virus infection model with time delay is discussed. By analyzing the corresponding characteristic equations, the local stability of each of the feasible equilibria of the model is studied. By using comparison arguments, it is proved that if the basic reproduction ratio is less than unity, the infection-free equilibrium is globally asymptotically stable. If the basic reproduction ratio is greater than unity, by means of an iteration technique, sufficient conditions are derived for the global asymptotic stability of the virus-infected equilibrium. Numerical simulations are carried out to illustrate the theoretical results.
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institution Kabale University
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publishDate 2010-01-01
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series Discrete Dynamics in Nature and Society
spelling doaj-art-66bcd1372cf34033833f9c5b3a5d18512025-02-03T06:11:07ZengWileyDiscrete Dynamics in Nature and Society1026-02261607-887X2010-01-01201010.1155/2010/182340182340Asymptotic Properties of a Hepatitis B Virus Infection Model with Time DelayXiaohong Tian0Rui Xu1Institute of Applied Mathematics, Shijiazhuang Mechanical Engineering College, No. 97 Heping West Road, Shijiazhuang 050003, ChinaInstitute of Applied Mathematics, Shijiazhuang Mechanical Engineering College, No. 97 Heping West Road, Shijiazhuang 050003, ChinaA hepatitis B virus infection model with time delay is discussed. By analyzing the corresponding characteristic equations, the local stability of each of the feasible equilibria of the model is studied. By using comparison arguments, it is proved that if the basic reproduction ratio is less than unity, the infection-free equilibrium is globally asymptotically stable. If the basic reproduction ratio is greater than unity, by means of an iteration technique, sufficient conditions are derived for the global asymptotic stability of the virus-infected equilibrium. Numerical simulations are carried out to illustrate the theoretical results.http://dx.doi.org/10.1155/2010/182340
spellingShingle Xiaohong Tian
Rui Xu
Asymptotic Properties of a Hepatitis B Virus Infection Model with Time Delay
Discrete Dynamics in Nature and Society
title Asymptotic Properties of a Hepatitis B Virus Infection Model with Time Delay
title_full Asymptotic Properties of a Hepatitis B Virus Infection Model with Time Delay
title_fullStr Asymptotic Properties of a Hepatitis B Virus Infection Model with Time Delay
title_full_unstemmed Asymptotic Properties of a Hepatitis B Virus Infection Model with Time Delay
title_short Asymptotic Properties of a Hepatitis B Virus Infection Model with Time Delay
title_sort asymptotic properties of a hepatitis b virus infection model with time delay
url http://dx.doi.org/10.1155/2010/182340
work_keys_str_mv AT xiaohongtian asymptoticpropertiesofahepatitisbvirusinfectionmodelwithtimedelay
AT ruixu asymptoticpropertiesofahepatitisbvirusinfectionmodelwithtimedelay