Asymptotic Properties of a Hepatitis B Virus Infection Model with Time Delay

A hepatitis B virus infection model with time delay is discussed. By analyzing the corresponding characteristic equations, the local stability of each of the feasible equilibria of the model is studied. By using comparison arguments, it is proved that if the basic reproduction ratio is less than uni...

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Bibliographic Details
Main Authors: Xiaohong Tian, Rui Xu
Format: Article
Language:English
Published: Wiley 2010-01-01
Series:Discrete Dynamics in Nature and Society
Online Access:http://dx.doi.org/10.1155/2010/182340
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Summary:A hepatitis B virus infection model with time delay is discussed. By analyzing the corresponding characteristic equations, the local stability of each of the feasible equilibria of the model is studied. By using comparison arguments, it is proved that if the basic reproduction ratio is less than unity, the infection-free equilibrium is globally asymptotically stable. If the basic reproduction ratio is greater than unity, by means of an iteration technique, sufficient conditions are derived for the global asymptotic stability of the virus-infected equilibrium. Numerical simulations are carried out to illustrate the theoretical results.
ISSN:1026-0226
1607-887X